Effect of addition of bioactive glass to resin modified glass ionomer cement on enamel demineralization under orthodontic brackets

Abstract

Background Enamel demineralization and white spot lesions around orthodontic brackets is a common problem associated with fixed orthodontic treatment. Glass ionomer cements (GICs) are commonly used for bracket bonding and recently, bioactive glass (BAG) was added to GICs to enhance deposition of calcium phosphate in adjacent dental structure. This study sought to assess the effect of addition of BAG particles to resin modified GIC (RMGIC) on enamel demineralization under orthodontic brackets. Material and Methods In this in vitro , experimental study, 60 sound human premolars were immersed in distilled water at 6°C. The teeth were randomly divided into three groups. Using a sticker, a window measuring 7x7 mm was created on the buccal surface. The remaining surfaces were coated with nail varnish twice with a 3-hour interval. After 24 hours, the stickers were removed. Brackets were bonded to tooth surfaces using Transbond XT (control), Fuji II LC RMGIC and Fuji II LC containing 30% BAG particles. To induce acid attacks, the teeth were immersed in demineralizing solution for 6 hours. For pH cycling, the teeth were then immersed in remineralizing solution for 18 hours. This process was repeated for 21 days. Next, the teeth were longitudinally sectioned into two halves and the depth of demineralization was measured from the deepest point to the surface under a polarized light microscope. Data were analyzed using one-way ANOVA, and pairwise comparisons were carried out using Tukey’s test. Results The mean depth of demineralization was 73.8±22.29, 118.08±29.42 and 182.98±20.69 µm in the BAG, RMGIC and Transbond XT groups, respectively. One-way ANOVA showed significant differences in terms of depth of demineralization among the three groups ( P =0.0001). Tukey’s test revealed significant differences in depth of demineralization. Conclusions Addition of BAG to RMGIC can significantly decrease the depth of enamel demineralization under orthodontic brackets in vitro . Key words: Remineralization, demineralization, orthodontic brackets, bioactive glass, resin modified glass ionomer cement.

Effect of Strontium-Doped Bioactive Glass on Preventing Formation of Demineralized Lesion

“…In another study, the reconstructed micro-CT images showed a reduced demineralization of dentine surface in the groups treated with fluoride products [ 23 ]. An in vitro study showed that the bioactive glass added into glass ionomer cement (GIC) can decrease the degree of enamel demineralization around orthodontic brackets [ 24 ], which is consistent with the results of the present study. An earlier study found that adding 45S5BAG fillers into sealants can prevent demineralization of enamel surfaces [ 25 ].…”

Evaluation of Surface Roughness of Composite, Compomer and Carbomer After Curing Through Mylar Strip and Glycerin: A Comparative Study

“…1 However, in pediatric practice, glass ionomer cements still maintain their vital role due to their remineralization effect on demineralized carious tissue. [2][3][4] A decade ago, nanofillers were integrated into glass ionomer cements and a new restoration material carbomer was developed. It was claimed to remineralize hydroxy apatite and form flouroapatite crystals.…”

Resin-Based Sealant with Bioactive Glass and Zwitterionic Material for Remineralisation and Multi-Species Biofilm Inhibition

“…BAG is an inorganic compound of biocompatible materials that reacts rapidly in an aqueous environment with the releases of ions, such as Ca 2+ , Na + , and PO 4 3− , which could aid in the remineralisation of the tooth structure [ 21 ]. According to Shimazi et al [ 50 ], BAG has a high ability to release ions due to its large surface and high properties due to weak ionic bonds. The easy release of calcium into the surrounding environment could inhibit demineralisation and promote remineralisation [ 19 ].…”