Effect of age on the performance of bispectral and entropy indices during sevoflurane pediatric anesthesia: a pharmacometric study

Abstract

Performance of both monitors improves as age increases. Our results suggest a need for the development of new monitor algorithms or calibration to better account for the age-specific EEG dynamics of younger patients.

The effect of xenon‐augmented sevoflurane anesthesia on intraoperative hemodynamics and early postoperative neurocognitive function in children undergoing cardiac catheterization: A randomized controlled pilot trial

“…Last, the profile of the EEG changes observed during xenon anesthesia was found to closely resemble those caused by propofol . Furthermore, although age‐related changes in BIS values in children were observed, it has been suggested that the BIS can be reliably used to monitor depth of anesthesia in children older than 1 year of age, showing better performance with increasing age . We therefore consider the BIS (together with interpretations of clinical signs) a valuable monitor of depth of anesthesia in our patient population.…”

“…Fahlenkamp et al 28 showing better performance with increasing age. 31,32 We therefore consider the BIS (together with interpretations of clinical signs) a valuable monitor of depth of anesthesia in our patient population.…”

Effect of xenon and dexmedetomidine as adjuncts for general anesthesia on postoperative emergence delirium after elective cardiac catheterization in children: study protocol for a randomized, controlled, pilot trial

“…Lastly, EEG changes observed during xenon anesthesia resembled closely those instigated by propofol [33]. Furthermore, although age-related changes in BIS values in children were observed, it has been suggested that the BIS is a reliable monitor of depth of anesthesia at least in children aged > 1 year, showing better performance with increasing age [34,35]. Note that in our study, the adequacy of depth of anesthesia will primarily be assessed by physiological signs (absence of HR or BP increases and involuntarily movements) and the BIS monitor is only an additional tool to quantify depth of anesthesia.…”

Effect of age on Narcotrend Index monitoring during sevoflurane anesthesia in children below 2 years of age

“…Jacknife method was used to calculate P k standard errors and hence confidence intervals. As previous published comparable studies including 30‐50 patients showed significant correlation of sevoflurane with the results of processed EEG‐monitoring, we decided to include at least 50 infants and children in this observational study.…”