Effect of alcohol consumption status and alcohol concentration on oral pain induced by alcohol-containing mouthwash

Abstract

Alcohol exposure alters oral mucosa.Patient compliance with mouthwash use may be reduced by oral pain resulting from rinsing with alcohol-containing mouthwash. However, information regarding the effects of alcohol consumption and mouthwash alcohol concentration on oral pain is limited. In this double-blind, randomized, controlled cross-over study, we investigated the effects of alcohol consumption status and mouthwash alcohol concentration on response to and perception of oral pain induced by alcohol-containing mouthwash. Fifty healthy men aged 33 to 56 years were enrolled and classified as drinkers and nondrinkers according to self-reported alcohol consumption. All subjects rinsed with two commercially available mouthwash products (which contained high and low concentrations of alcohol) and a negative control, in randomized order. Time of onset of oral pain, time of cessation of oral pain (after mouthwash expectoration), and pain duration were recorded, and oral pain intensity was recorded on a verbal rating scale. Drinkers had later oral pain onset and lower pain intensity. High-alcohol mouthwash was associated with earlier pain onset and greater pain intensity. In addition, oral pain cessation was later and pain duration was longer in nondrinkers rinsing with high-alcohol mouthwash. In conclusion, alcohol consumption status and mouthwash alcohol concentration were associated with onset and intensity of oral pain. (J Oral Sci 55, 99-105, 2013)

Effect of mouth rinses on tooth enamel surface

“…This result is similar to those of previously performed in vitro studies [5,[9][10][11][12][13]. It found significant changes to tooth enamel surfaces subjected to mouth rinse and, in addition, products containing alcohol may induce changes to oral tissues [3].…”

“…Over-the-counter (OTC) refers to products that are sold freely to consumers in supermarkets, drugstores, convenience stores, and on the Internet. This type of product does not require a prescription or professional application [1][2][3][4][5] because it is self-applicable and can be found in various presentations, such as whitening dentifrices, mouth rinses, chewing gum, and paint-on films. [1,2,6].…”

Comparison of the in vitro Effect of Chemical and Herbal Mouthwashes on Candida albicans

“…Candida albicans is considered as part of the normal flora of the mouth, which doesn’t cause disease but under unfavorable local conditions, such as poor oral hygiene ( 1 ), wearing of denture ( 2 ) and general predisposing factors such as high carbohydrate diet, smoking ( 3 ), diabetes ( 4 ) malnutrition, leukemia, chemotherapy, genetic disorders ( 5 ), long term antibiotic therapy ( 6 ), corticosteroid therapy ( 7 ), senility ( 8 ), radiotherapy ( 9 ) and cancer ( 10 )can cause candidiasis. Using mouthwashes is a common way to controlling the C. albicans population in the mouth, which are used widely in dentistry ( 11 , 12 ). Mouthwashes have been recommended for the prevention and control of oral diseases, especially for the control of oral microorganisms ( 13 ).…”

Effect of herbal mouthrinses on dental plaque formation and gingival inflammation: A systematic review

“…Currently, a wide range of commercial products is available in the form of toothpastes and mouthrinses to inhibit the growth of dental plaque and gingival inflammation. However, many of these formulations contain alcohol, that the long‐term adverse effects are not know (Cole, Rodu, & Mathisen, 2003; Satpathy et al, 2013; Zamora‐Perez et al, 2013), and some agents, such as chlorhexidine (CHX), have several adverse effects (Van Strydonck et al, 2012).…”