Effect of Alcoholic Extract of Salvia officinalis Leaves on some Physiological Parameters Aspects in Acrylamide-Treated Rats

Khudiar, Khalisa Khadim; Hussein, Ghasag Jawad

doi:10.14737/journal.aavs/2017/5.1.47.55

Cited by 3 publications

(2 citation statements)

References 54 publications

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“…Our findings revealed that addition of SP and SO in the diet of Nile tilapia elevated the level of serum IgM. Those findings are in the same direction with those noted after SP [69] and SO [70] supplementation.…”

Section: Antibodiessupporting

confidence: 88%

Evaluation of Immunostimulant Activity of Spirulina platensis (Arthrospira platensis) and Sage (Salvia officinalis) in Nile Tilapia (Oreochromis niloticus)

Abdellatief

Rahman

Abdallah

2018

Zagazig Veterinary Journal

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Immunostimulants have been found to be attractive and promising agents for disease management in aquaculture. The current study aimed to assess the impacts of feeding with Spirulina platensis (SP) and Salvia officinalis (SO) for 28 days on the immune status of Nile tilapia (Oreochromis niloticus). A total of 180 Nile tilapia (30.6 ± 0.12 g) were divided into 3 groups (triplicates of 20 fish/group). Control group was fed on a basal diet only, while the other two groups were supplemented with SP (10 gm/kg diet) and SO (7.5 gm/kg diet) respectively. Both of SP and SO showed in vitro antimicrobial activity against Pseudomonas aeruginosa. The immune response of Nile tilapia supplemented with SP and SO revealed significant increases in lysozyme, nitric oxide activities and IgM titer with enhancement of IL-1β and TNF-α genes expression before and after infection with P. aeruginosa. Fish challenged with P. aeruginosa showed signs of infection with high mortality rate and low relative percentage survival which elevated to be 83% in SP group and 75% in SO group. It could be concluded that dietary supplementation with SP and SO improved immune response and protected Nile tilapia against infection. Moreover, SP showed better results than SO before and after infection.

show abstract

Section: Antibodiessupporting

confidence: 88%

Evaluation of Immunostimulant Activity of Spirulina platensis (Arthrospira platensis) and Sage (Salvia officinalis) in Nile Tilapia (Oreochromis niloticus)

Abdellatief

Rahman

Abdallah

2018

Zagazig Veterinary Journal

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“…Smoke from cigarettes and meals high in carbs that have been cooked at high temperatures both contain high levels of Acrylamide (Bušová et al, 2022). It was believed that Acrylamide exposure only happened at work in industrial field, however, drinking polluted water, using cosmetics, and cigarette smoking all contributed to its exposure (Khudiar and Hussein, 2017). Additionally, the chemical building block Acrylamide, which is used to make polyacrylamide , may be modified to have nonionic, anionic, or cationic properties for certain applications (González et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

The Neuroprotective Effect of Curcumin Cumin Against Oxidative Stress- Induced by Acrylamide in Male Rats

Hayder Khayoon,

Ahmed Abdulwahid

2023

AAVS

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Rats exposed to Acrylamide )ACR( displayed a neurotoxicity and alteration in behaviors. Curcumin (CUR) is useful in reducing behavioral flaws and restoring a normal body systems' function. The goal of the current study is to evaluate the how the brain effected oxidatively by Acrylamide exposure and the ability of Curcumin to ameliorate the neurotoxicity. For this investigation, thirty mature male albino rats be used, (10/group), the control group (CC), animals were intubated with distilled water for 40 days, Group G1, rats received Acrylamide 5 mg/kg B.W. every day for 40 days by gavage needle, and Group G2, in this group animals got Acrylamide 5 mg/kg B.W. and Curcumin 100 mg/kg B.W. for 40 days by gavage needle as well. At the zero and the end times of the experiment, blood samples were taken using the heart puncture technique after the subjects had been given an intramuscular injection of ketamine and xylazine to induce anesthesia. The findings revealed the exposure of Acrylamide to rats significantly reduced their tendency to gain weight, a marked rise in the concentration of malondialdehyde and decrease levels of Total antioxidant in blood serum and behavioral differences like Acrylamide greatly decreased the struggling and ascending time in the swimming test, dramatically lengthens the time needed to turn an animal's head 180 degrees during a negative geotaxis test and decreased locomotors activity in the Y maze test. Curcumin's anti-apoptotic, anti-inflammatory, and antioxidant properties have not been thoroughly examined in neurotoxicity given on by Acrylamide, nevertheless. We investigated whether Curcumin may protect against oxidative stress, apoptosis, and inflammation in neurons brought on by Acrylamide exposure. In conclusion acrylamide alters the neurobehaviors and oxidatively stressed animals .However Curcumin restored these parameters close to control values.

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Acrylamide, the Unnatural Compound: Exposure and Toxicity on Humans and Animals

Zouhairi,

Kahloula,

Adli Djallal Eddine

et al. 2022

Nutrition and Human Health

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Effect of Alcoholic Extract of Salvia officinalis Leaves on some Physiological Parameters Aspects in Acrylamide-Treated Rats

Cited by 3 publications

References 54 publications

Evaluation of Immunostimulant Activity of Spirulina platensis (Arthrospira platensis) and Sage (Salvia officinalis) in Nile Tilapia (Oreochromis niloticus)

Evaluation of Immunostimulant Activity of Spirulina platensis (Arthrospira platensis) and Sage (Salvia officinalis) in Nile Tilapia (Oreochromis niloticus)

The Neuroprotective Effect of Curcumin Cumin Against Oxidative Stress- Induced by Acrylamide in Male Rats

Acrylamide, the Unnatural Compound: Exposure and Toxicity on Humans and Animals

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