Effect of “Amprolinsyl” and “Amprolium 22%” on morphological indices of blood of turkeys for eumeria invasion

Abstract

The article gives data on the influence of Amprolinsyl and Amprolium 22% on morphological parameters of blood after eumirioic invasion. It has been shown that after application of amprolium 22% for the treatment of turkeys infected with eumeria invasion, gradual normalization of hematological parameters of blood begins. Thus, at the 3rd day of treatment, the number of red blood cells increased, but remained 25.1% lower, and the hemoglobin level increased, but remained at 16.3% lower, compared with clinically healthy poultry. During this period, within the limits of normal values was the value of the color index, the mass of hemoglobin in the erythrocyte and the value of hematocrit. The obtained results indicate a gradual normalization of the erythropoietic function of the bone marrow. However, the large average volume of one erythrocyte is 1.12 ± 0.07 μm against 0.96 ± 0.03 μm³ in the control, and the decrease in the average concentration of hemoglobin in one erythrocyte by 13.3% against the norm indicates an incomplete recovery of the erythropoietic bone marrow function. At day 5 of treatment with amprolium, 22% of red blood cells and hemoglobin levels increased but still remained below physiological values by 12.3% and 6.8%, respectively, compared to control. At the 10th day of the experiment, restoration of hematopoietic function of the bone marrow was observed on physiological values of erythrocytes and hemoglobin content of the blood, as well as blood leukogram. In the treatment of turkeys with "Amprolisyl", at the 5th day, the hematopoietic function of the bone marrow completely normalized, as indicated by the number of red blood cells, hemoglobin content and red blood cell index values. It is known that the values of red blood cells, namely the volume of erythrocytes, the mass and concentration of hemoglobin in them, and the color index objectively reflect the state of hematopoietic function of the bone marrow. The results of our studies indicate that in the turkey infected with imeiriosis and treated with amprolium 22%, clinical recovery occurs at day 5, and the hematopoietic function of the bone marrow is restored spontaneously in 5 days after recovery. In the treatment of turkeys with Amprolinsyl, the restoration of morphological parameters, the normalization of white blood cell leukemogram and the clinical recovery of turkeys arose on the fifth day of treatment. Thus, due to the fact that Amporolinsyl, in addition to the active ingredient, contains sparse fruit of thistle spots, which contain high levels of vitamins A and K, and trace elements – Ferum, Kuprum and Cobalt, which are directly involved in hemopoiesis, therefore, the restoration of hematopoietic function of the bone marrow comes much faster than with the application of amprolium itself 22%.

Toxic effects of various zinc dosages on poultry hemopoiesis

“…Thus, the results of the study showed zinc poisoning of chickens even within 1-3 days led to damage to bone marrow cells. The cytoplasm of blood-forming and stromal cells of the bone marrow detects mostly signs of destructive processes, which are amplified as the duration and the dose of exposure increase [7]. At the same time, the structure of cell nuclei often gets changed in the bone marrow.…”

Органолептичні Показники Та Хімічний Склад М’яса Індиків За Наявності «наминів» Кіля

“…Її рекомендують як корисний продукт у лікувальному та дієтичному харчуванні. Усі вказані чинники роблять цей вид м'яса доволі конкурентоспроможним порівняно із м'ясом інших видів птиці та забійних тварин [10,12,18].…”

Effect of fenbenzyl and fenbendazole on peroxide intensity oxidation of lipids in the blood of dogs in experimental toxocariasis

“…Деякими вченими було встановлено складність патогенезу токсокарозу у тварин: розлади обміну речовин, порушення фізіологічних функцій організму, також було запропоновано різні способи лікування тварин за даної патології. Зокрема, досі залишається не виясненим питання про вплив токсокар та їх метаболітів на одну з важливих, захисних систем організму -антиоксидантну систему, завданням якої є підтримання балансу між інтенсивністю радикалоутворення та потребами організму у фізіолого-біохімічних аспектах дії радикалів кисню та їх похідних, а саме синтезу біологічно-активних речовин, регуляції проникності мембран (Stybel et al, 2019;Grymak et al, 2020;Varkholiak et al, 2021).…”