Effect of an antioxidant functional food beverage on exercise-induced oxidative stress: A long-term and large-scale clinical intervention study

Muñoz, Mauricio Pastor; Galán, A.I.; Palacios, Encarna; Díez, María Ángeles Llorca; Muguerza, Begoña; Cobaleda, César; Calvo, Jose Ignacio; Aruoma, Okezie I.; Sánchez-Garcı́a, Isidro; Jiménez, Rafael

doi:10.1016/j.tox.2009.10.015

Cited by 18 publications

(10 citation statements)

References 55 publications

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“…8-OHdG was significantly lower in a moderate endurance exercise group than in a sedentary group4 ) . After 10 months of aerobic exercise, the 8-OHdG level was increased significantly compared to the baseline in a group of elderly subjects23 ) . Inconsistency among these outcomes may be due to the different age groups, exercise types and modes, as well as the exercise intervention duration.…”

Section: Discussionmentioning

confidence: 96%

Tai Chi Improves Oxidative Stress Response and DNA Damage/Repair in Young Sedentary Females

et al. 2014

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[Purpose] This study was to examine the effects of 12 weeks of Tai Chi (TC) exercise on antioxidant capacity, and DNA damage/repair in young females who did not perform regular physical exercise. [Subjects and Methods] Ten female students from a Chinese university voluntarily participated in this program. All of them practiced the 24-form simplified Tai Chi, 5 times weekly, for 12 weeks. Plasma levels of superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA), glutathione (GSH), hydroxyl radical inhibiting capacity (OH·-IC), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-oxoguanine DNA glycosylase (OGG1) were measured at 0, 8, and 12 weeks. Heart rate (HR) was monitored during the last set of the training session at 4, 8, and 12 weeks. [Results] Plasma SOD and OH·-IC levels were increased at 8 and 12 weeks compared to the baseline (0 weeks). Gpx and GSH levels did not change significantly throughout the study period. The plasma MDA level was decreased significantly at 8 weeks but not at 12 weeks compared to the baseline value. While the plasma 8-OHdG level did not change throughout the study period, the plasma OGG1 level was significantly increased at 8 and 12 weeks compared to the baseline value. [Conclusion] TC practice for 12 weeks efficiently improved the oxidative stress response in young females who did not perform regular physical exercise. The TC exercise also increased the DNA repairing capacity.

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Section: Discussionmentioning

confidence: 96%

Tai Chi Improves Oxidative Stress Response and DNA Damage/Repair in Young Sedentary Females

et al. 2014

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“…El organismo parece ser capaz de soportar un incremento limitado de radicales libres, de hecho algunos datos sugieren que es necesario un aumento en las especies oxigeno-reactivas (ROS) para que ocurra una adaptación muscular al ejercicio 35,36 . Aunque no se encontraron estudios que evaluaran la relación entre la suplementación de antioxidantes y función gastrointestinal en atletas, diversos autores sugieren que un aumento en la producción de ROS puede ser deletérea para la función gastrointestinal y por lo tanto sugieren que los deportistas en riesgo deberían llevar un control frecuente de los niveles de vitaminas y determinar si se pueden beneficiar de la suplementación 35,37 .…”

Section: Antioxidantesunclassified

Estrategias de suplementacion y función gastrointestinal en atletas de resistencia

Duarte

Giménez-Sánchez²

2015

Rev Esp Nutr Hum Diet

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La prevalencia de síntomas gastrointestinales en el atleta de resistencia oscila entre el 25% y el 70%. Aunque se reconoce que la etiología del dolor abdominal durante el ejercicio es multifactorial, la redistribución del flujo sanguíneo y por lo tanto la isquemia gastrointestinal (GI) son frecuentemente reconocidos como los principales mecanismos fisiopatológicos mediante los cuales se altera la función de la barrera intestinal y en consecuencia se presentan los sínto-mas. Esta revisión evalúa los mecanismos fisiopatológicos que afectan la función de la barrera intestinal en consecuencia al ejercicio intenso y prolongado, y analiza diferentes nutrientes y/o fitoquímicos que pueden mejorar o mantener la función de la barrera intestinal en atletas de resistencia y ultrarresistencia en pedestrismo. Se analizan diferentes nutrientes que podrían mejorar la perfusión esplácnica durante el ejercicio, reducir o mejorar la disfunción de la pared gastrointestinal, encontrando que a pesar de que existen algunos estudios en el área, la evidencia científica no respalda su uso en población deportista.

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“…Pharmaceutical drugs such as benzodiazepines and selective serotonin reuptake inhibitors are regularly prescribed for anxiety, stress, and depression but are often associated with serious side effects, a fact that has led to the demand for nutraceutical alternatives to combat the effects of stress while supporting the body's natural ability to respond to stress. Supplements utilizing fish oil, Ginkgo biloba, and ginseng, as well as several vitamins and minerals, have routinely been shown to positively impact mental health and to modulate oxidative stress during exercise (8,9). Given the wide range of factors that influence stress, as well as the multiple indications through which stress can manifest itself, a combinatory strategy that uses a carefully selected nutraceutical formulation-providing multiple vitamins, minerals, amino acids, and naturally sourced ingredients-may represent a valid course of action.…”

Section: Introductionmentioning

confidence: 99%

A Randomized Double-Blind, Placebo Controlled, Four-Arm Parallel Study Investigating the Effect of a Broad-Spectrum Wellness Beverage on Mood State in Healthy, Moderately Stressed Adults

Evans¹,

Antony²,

Guthrie³

et al. 2018

Journal of the American College of Nutrition

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Effect of an antioxidant functional food beverage on exercise-induced oxidative stress: A long-term and large-scale clinical intervention study

Cited by 18 publications

References 55 publications

Tai Chi Improves Oxidative Stress Response and DNA Damage/Repair in Young Sedentary Females

Tai Chi Improves Oxidative Stress Response and DNA Damage/Repair in Young Sedentary Females

Estrategias de suplementacion y función gastrointestinal en atletas de resistencia

A Randomized Double-Blind, Placebo Controlled, Four-Arm Parallel Study Investigating the Effect of a Broad-Spectrum Wellness Beverage on Mood State in Healthy, Moderately Stressed Adults

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