Background
The World Health Organization (WHO) estimates that the number of
obese or overweight individuals worldwide will increase to 1.5 billion by
2015. Chronic diseases associated with overweight or obesity include
diabetes, heart disease, hypertension and stroke.
Objectives
To assess the effects of interactive computer-based interventions for
weight loss or weight maintenance in overweight or obese people.
Search methods
We searched several electronic databases, including CENTRAL, MEDLINE,
EMBASE, CINAHL, LILACS and PsycINFO, through 25 May 2011. We also searched
clinical trials registries to identify studies. We scanned reference lists
of included studies and relevant systematic reviews.
Selection criteria
Studies were included if they were randomized controlled trials or
quasi-randomized controlled trials that evaluated interactive computer-based
weight loss or weight maintenance programs in adults with overweight or
obesity. We excluded trials if the duration of the intervention was less
than four weeks or the loss to follow-up was greater than 20%
overall.
Data collection and analysis
Two authors independently extracted study data and assessed risk of
bias. Where interventions, control conditions, outcomes and time frames were
similar between studies, we combined study data using meta-analysis.
Main results
We included 14 weight loss studies with a total of 2537 participants,
and four weight maintenance studies with a total of 1603 participants.
Treatment duration was between four weeks and 30 months. At six months,
computer-based interventions led to greater weight loss than minimal
interventions (mean difference (MD) −1.5 kg; 95% confidence
interval (CI) −2.1 to −0.9; two trials) but less weight loss
than in-person treatment (MD 2.1 kg; 95% CI 0.8 to 3.4; one trial).
At six months, computer-based interventions were superior to a minimal
control intervention in limiting weight regain (MD −0.7 kg;
95% CI −1.2 to −0.2; two trials), but not superior
to infrequent in-person treatment (MD 0.5 kg; 95% −0.5 to
1.6; two trials). We did not observe consistent differences in dietary or
physical activity behaviors between intervention and control groups in
either weight loss or weight maintenance trials. Three weight loss studies
estimated the costs of computer-based interventions compared to usual care,
however two of the studies were 11 and 28 years old, and recent advances in
technology render these estimates unlikely to be applicable to current or
future interventions, while the third study was conducted in active duty
military personnel, and it is unclear whether the costs are relevant to
other settings. One weight loss study reported the cost-effectiveness ratio
for a weekly in-person weight loss intervention relative to a computer-based
intervention as USD 7177 (EUR 5678) per life year gained (80% CI USD
3055 to USD 60,291 (EUR 2417 to EUR 47,702)). It is unclear whether this
could be extrapolated to other studies. No data were identified on adverse
events, morbidity, complications or health-rel...