Effect of Andrographolide on Foam Cell Formation at the Initiation Stage of Atherosclerosis

Abstract

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Novel wine in an old bottle: Preventive and therapeutic potentials of andrographolide in atherosclerotic cardiovascular diseases

“…Meanwhile, there was almost no plaque accumulation in the aortic root of apolipoprote E-deficient (ApoE −/− ) mice after AG treatment (1 and 2.5 mg/kg) [ 122 ]. In addition, AG (40 mg/kg) reduced the accumulation of foam cells in atherogenic diet induced rat aortic lesions [ 123 , 124 ].…”