Effect of Angle Narrowing on Sectoral Variation of Anterior Chamber Angle Width

Xu, Benjamin; Pardeshi, Anmol A.; Shan, Jing; DeBoer, Charles; Moghimi, Sasan; Richter, Grace M.; McKean‐Cowdin, Roberta; Varma, Rohit

doi:10.1016/j.ogla.2019.12.005

Cited by 7 publications

(2 citation statements)

References 24 publications

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“…16 Therefore, AS-OCT measurements, which reflect anatomic and physiologic changes related to angle closure, could complement gonioscopy to refine the management of early stage PACD. 17,18 In this study, we assess the intradevice repeatability and interdevice agreement of measurements by the Tomey CASIA SS-1000, a device on which many key studies on angle closure were conducted, and the newly commercialized and Conformité Européene (CE) marked Heidelberg ANTERION. Comparing measurements within and between these two devices is crucial since previous AS-OCT devices have demonstrated variable interdevice measurement agreement, ranging from poor to excellent.…”

Section: Introductionmentioning

confidence: 99%

Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices

Pardeshi

Song

Lazkani

et al. 2020

Trans. Vis. Sci. Tech.

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To assess the repeatability and agreement of ocular biometric parameters measured using the Tomey CASIA SS-1000 and Heidelberg ANTERION anterior segment optical coherence tomography (AS-OCT) devices. Methods: Both eyes of subjects 18 years of age or older were scanned three times with the CASIA and ANTERION under standardized dark lighting. One AS-OCT image along the horizontal (temporal-nasal) meridian was analyzed per eye and per scan. Pupillary diameter (PD) was within 15% for all pairwise comparisons. Anterior chamber depth, lens vault, anterior chamber width, angle opening distance, trabecular iris space area, and scleral spur angle (SSA500) were measured using manufacturer-provided image analysis software. Intraclass correlation (ICC), Wilcoxon signed-rank, and Bland-Altman analyses were performed to assess intradevice repeatability and interdevice agreement of measurements. Results: Thirty-two eyes of 21 subjects were analyzed. There was excellent agreement (ICC >0.98) and no significant difference (P > 0.05) in PD across all comparisons. Intradevice measurement repeatability was excellent for both the CASIA (ICC range 0.93-0.99) and ANTERION (ICC range 0.97-0.99). Interdevice measurement agreement was also excellent (ICC range 0.85-0.96). Measurements within and between devices were similar (P > 0.06) for all parameters except SSA500 (P = 0.03). Linear regression and Bland-Altman plots showed the relationship was consistent across the entire range of measurements. Conclusions: Intradevice measurement repeatability is excellent for the CASIA and ANTERION. Interdevice measurement agreement between the two devices exceeds metrics reported by previous comparison studies. Translational Relevance: Modern swept-source AS-OCT devices produce highly repeatable measurements of ocular biometric parameters that are nearly interchangeable across devices. has steadily advanced over the past two decades. 1-3 Early time-domain AS-OCT devices, such as the Zeiss Visante (Carl Zeiss Meditec, Dublin, CA), were slow and produced low-quality images compared to modern Fourier-domain optical coherence tomography (OCT) devices. While spectral-domain OCT devices, such

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Section: Introductionmentioning

confidence: 99%

Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices

Pardeshi

Song

Lazkani

et al. 2020

Trans. Vis. Sci. Tech.

Self Cite

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“…4,13 Previous studies have reported that the superior and inferior angles are anatomically narrower and are associated with more variable iris insertions than the nasal and temporal ones. [14][15][16][17] So, we opted for examining the nasal and temporal angles to have more reproducible results and to avoid statistical bias.…”

Section: Methodsmentioning

confidence: 99%

Nasal trabeculo-ciliary angle and relative lens vault as predictors for intraocular pressure reduction following phacoemulsification

Allam

Raafat

Elmohsen

2021

European Journal of Ophthalmology

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Purpose To evaluate quantitative relationships between biometric measurements and expected intraocular pressure reduction following phacoemulsification. Design A prospective, comparative clinical study. Methods Forty nine candidates for phacoemulsification were included. Intraocular pressure was measured preoperatively and after 7 and 30 days. Ocular biometrics were measured using optical biometry and ultrasound biomicroscopy preoperatively and 1 month postoperatively. Results Patients were sub-grouped into open-angle glaucoma (12 eyes), angle-closure glaucoma (18 eyes), and cataract-only groups (19 eyes). The mean intraocular pressure reduction was −1.67 ± 2.73, −13.11 ± 7.98, and −7.50 ± 3.58 mmHg in the cataract-only, angle-closure glaucoma, and open-angle glaucoma groups ( p = 0.001). The delta-intraocular pressure at day 7 showed positive correlations with lens vault and relative-lens vault ( p = 0.005 and 0.001). It showed negative correlations with lens position, relative-lens position, anterior chamber depth, aqueous depth, and nasal and temporal angles in addition to lens thickness, anterior vault, nasal trabeculo-ciliary angle, and temporal-trabeculo-ciliary angle at the end of the follow-up period. Regression analysis revealed significant associations between preoperative intraocular pressure and both nasal-trabeculo-ciliary angle and anterior vault ( p = 0.038 and 0.019) and delta-intraocular pressure and both nasal-trabeculo-ciliary angle and relative-lens vault ( p = 0.001 and ≤0.001) with an area under the curve of 0.71 for relative-lens vault. For every degree decrease in nasal-trabeculo-ciliary angle, there was an expected 0.33 mmHg intraocular pressure reduction with no expected change if nasal-trabeculo-ciliary angle decreased to <22°. Conclusions The relationship between anterior-segment-biometrics could determine intraocular pressure behavior after phacoemulsification. The preoperative nasal-trabeculo-ciliary angle and relative-lens vault could be significant predictors for postoperative intraocular pressure reduction.

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Role of Static and Dynamic Ocular Biometrics Measured in the Dark and Light as Risk Factors for Angle Closure Progression

Cho

Friedman

et al. 2023

American Journal of Ophthalmology

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Effect of Angle Narrowing on Sectoral Variation of Anterior Chamber Angle Width

Cited by 7 publications

References 24 publications

Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices

Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices

Nasal trabeculo-ciliary angle and relative lens vault as predictors for intraocular pressure reduction following phacoemulsification

Role of Static and Dynamic Ocular Biometrics Measured in the Dark and Light as Risk Factors for Angle Closure Progression

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