Effect of antibiotics on pancreatic enzymes of rats fed soybean flour

Goldberg, Ada; Guggenheim, K.

doi:10.1016/0003-9861(64)90383-2

Cited by 16 publications

(8 citation statements)

References 22 publications

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“…The methionine and antibiotics supplementation caused similar changes in the pancreatic enzymes as those obtained on unsupplemented raw soybean diet. These results are contradictory to those of Goldberg and Guggenheim (1964) who reported the direct action of antibiotics on pancreas in lowering the fall of trypsin and amylase. Methionine and antibiotics added to the diet with raw soybeans did not alter the changes in pancreatic enzyme brought about by raw soybeans alone.…”

contrasting

confidence: 82%

Biochemical Changes in the Pancreases of Chicks Fed Raw Soybeans and Soybean Meal

et al. 1967

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contrasting

confidence: 82%

Biochemical Changes in the Pancreases of Chicks Fed Raw Soybeans and Soybean Meal

et al. 1967

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“…The basal diet, excluding protein sources, was composed (in %) of maize starch 91, vegetable oil 5 and salt mixture (USP XIV) 4. Appropriate amounts of maize starch were replaced by sbf or groundnut meal to give diets containing 9 or 18% protein.…”

Section: Methodsmentioning

confidence: 99%

“…One of the actions of the trypsin in hibitor relates to the pancreas. Feeding raw sbf or direct treatment results in a hypertrophy of the pancreas and stimulates pancreatic secretion leading to a loss of endogenous protein [3][4][5][6][7]. No informa tion appears to be available on the effect of sbf on the endocrine secretion of the pancreas.…”

mentioning

confidence: 99%

Changes in Carbohydrate Metabolism in Rats Fed Raw Soybean Flour

Goldberg¹

1970

Ann Nutr Metab

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Young rats were fed diets containing unheated or heat-processed soybean flour as source of protein. Weight gain and food intake were lower and pancreatic weight in relation to body weight, higher in rats adapted to unheated soybean flour. Rats adapted to unheated soybean flour exhibited some deviations from normal carbohydrate metabolism. Following a load of glucose they accumulated more glycogen in their livers and responded with a higher blood glucose level. Their pancreases secreted in vitro more ‘insulin like activity’ and glucagon. When food intake of rats adapted to heated soybean flour was restricted to the amounts eaten by rats adapted to unheated soybean flour, these differences in carbohydrate metabolism disappeared. It is concluded that the deviations observed are rather the results of restricted food intake than a specific effect of soybean trypsin inhibitor.

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“…Other investigators have reported that low levels of antibiotics (0.02 percent) improve the growth rate , or protein efficiency (Goldberg and Guggenheim, 1964). The level of raw soybeans in the rations may account for the differences in these observations.…”

Section: Hemagglutinin Factor In Raw Soybeansmentioning

confidence: 48%

“…Goldberg and Guggenheim (1964) noted an effect of penicillin within one hour after its ingestion or parenteral injection. They fed 100 gm.…”

Section: Hemagglutinin Factor In Raw Soybeansmentioning

confidence: 99%