Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat

Borazan, Mehmet; Karalezlı, Aylin; Akman, Ahmet; Akova, Yonca A.

doi:10.1016/j.jcrs.2007.06.046

Cited by 22 publications

(29 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[20][21][22][23] In our study, the effectiveness of dorzolamide-timolol maleate combination was not different from that of oral acetazolamide.…”

Section: Discussioncontrasting

confidence: 43%

“…There was no statistically significant difference between two groups (p=0.924). The mean postoperative IOP (1 st day) of the first group was 15.27±2.90 (SD) (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) mmHg and that of the second group was 14.82±2.57 (SD) (11-23) mmHg. There was no statistically significant difference between two groups (p=0.505).…”

Section: Resultsmentioning

confidence: 97%

“…and that of the second group was 14.67±2.77 (SD) (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21) mmHg (p=0.924). The mean postoperative IOP(1 st day) of the first group was 15.27±2.90 (SD) (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) mmHg and that of the second group was 14.82±2.57 (SD) (11-23) mmHg (p=0.505). The mean postoperative IOP (1 st week) of the first group was 13.72±2.44 (SD) (10-18) mmHg and that of the second group was 13.64±2.53 (SD) (10)(11)(12)(13)(14)(15)(16)(17)(18)(19) mmHg (p=0.895).…”

Section: Comparison Of Efficacy and Safety Of Topical Dorzolamide-timmentioning

confidence: 95%

See 2 more Smart Citations

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Çetinkaya¹,

Akçam²,

Gürdağ³

et al. 2015

Turkiye Klinikleri J Ophthalmol

View full text Add to dashboard Cite

A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To compare the efficacy and safety of topical dorzolamide-timolol maleate combination with oral acetazolamide for prevention of intraocular pressure rise following phacoemulsification surgery. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Sixty-seven eyes of 67 patients with cataracts (33 males, 34 females) who had undergone phacoemulsification and intraocular lens implantation surgery were evaluated retrospectively. Patients were divided into two groups. Group 1 comprised 33 (49%) patients who received oral acetazolamide 250 mg (Diazomid 250 mg tb) 1 hour before the surgery and 1hour after surgery and 125 mg 3 times a day for 3 days following surgery. Group 2 comprised 34 (51%) patients who received topical dorzolamidetimolol maleate combination 1 drop 1 hour before the surgery and twice a day for 3 days following surgery. R Re es su ul lt ts s: : The mean preoperative intraocular pressure (IOP) of the first group was 14.60±3.21 standard deviation (SD) (range 10-21) mmHg. and that of the second group was 14.67±2.77 (SD) (11-21) mmHg (p=0.924). The mean postoperative IOP(1 st day) of the first group was 15.27±2.90 (SD) (11-23) mmHg and that of the second group was 14.82±2.57 (SD) (11-23) mmHg (p=0.505). The mean postoperative IOP (1 st week) of the first group was 13.72±2.44 (SD) (10-18) mmHg and that of the second group was 13.64±2.53 (SD) (10-19) mmHg (p=0.895). C Co on nc cl lu us si io on n: : For prophylaxis of postoperative IOP rise after an uneventful cataract surgery, topical-dorzolamid timolol maleate combination and oral acetazolamide therapy have similar effects, however the adverse effects of systemic acetazolamide should be taken into account. Therefore it is better to prefer topical dorzolamide-timolol maleate combination therapy. K Ke ey y W Wo or rd ds s: : Phacoemulsification; intraocular pressure; acetazolamide; dorzolamide-timolol combination Ö ÖZ ZE ET T A Am ma aç ç: : Fakoemülsifikasyon cerrahisi sonrası artan göziçi basıncını azaltmak için kullanılan ağızdan verilen asetazolamid ile damla şeklinde uygulanan dorzolamid-timolol maleat kombinasyonunun etkinlik ve güvenilirliğinin kıyaslanmasıdır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Kataraktı olan ve fakoemülsifikasyon ve göziçi mercek (GİM) implantasyon cerrahisi geçiren 67 (33 erkek, 34 kadın) hastanın 67 gözü retrospektif olarak değerlendirildi. Hastalar iki gruba ayrıldılar. 1. grup 33 (%49) hastadan oluşmaktaydı, bu gruptaki hastalara ameliyattan 1 saat önce ve 1 saat sonra ağızdan 250 mg asetazolamid (toplam 500 mg) verildi ve ameliyattan sonraki 3 gün boyunca da 125 mg asetazolamid 3x1 önerildi. 2. grup 34 (%51) hastadan oluşmaktaydı, bu gruptaki hastalara ameliyattan 1 saat önce 1 damla dorzolamid-timolol maleat kombinasyonu uygulandı ve ameliyattan sonraki 3 gün boyunca da damla şeklinde dorzolamid-timolol maleat kombinasyonu 2x1 şek-linde önerildi. B Bu ul lg gu ul la ar r: : 1. grubun ortalama ameliyat öncesi göziçi basınç değeri 14,60±3,21 (SD)...

show abstract

“…[20][21][22][23] In our study, the effectiveness of dorzolamide-timolol maleate combination was not different from that of oral acetazolamide.…”

Section: Discussioncontrasting

confidence: 43%

Section: Resultsmentioning

confidence: 97%

Section: Comparison Of Efficacy and Safety Of Topical Dorzolamide-timmentioning

confidence: 95%

See 1 more Smart Citation

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Çetinkaya¹,

Akçam²,

Gürdağ³

et al. 2015

Turkiye Klinikleri J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…This can be avoided by administering oral acetazolamide or topical pressure-lowering agents in the immediate and early post-operative period. 24 Practice varies in different departments: a survey conducted in the UK showed that one-third of surgeons routinely used a pressure-lowering agent, and in most cases this was oral acetazolamide. 25 Some surgeons are more likely to use such agents in patients in whom IOP control is more critical, such as those with advanced glaucoma, as it has been suggested that glaucoma patients may be more likely to develop a rise in IOP.…”

Section: Raised Intraocular Pressurementioning

confidence: 99%

Complications of cataract surgery

Chan

Mahroo

Spalton

2010

Clinical and Experimental Optometry

137

View full text Add to dashboard Cite

Modern cataract surgery is safe in more than 95 per cent of patients. In the small number of cases where a serious complication occurs, the most common is an intra-operative posterior capsular rupture. This can lead to vitreous loss or a dropped nucleus and can increase the risk of post-operative cystoid macular oedema or retinal detachment. Postoperatively, posterior capsular opacification is the most common complication and can be readily treated with a YAG capsulotomy. The most devastating complication is endophthalmitis, the rate of which is now significantly decreased through the use of intracameral antibiotics. As a clinician, the most important step is to assess the patient pre-operatively to predict higher risk individuals and to counsel them appropriately. In these patients, various pre-or intra-operative management steps can be taken in addition to routine phacoemulsification to optimise their visual outcome.

show abstract

“…1,4 The problem with the vast majority of the studies that have investigated prophylaxis regimes for a raised IOP is that they have excluded patients suffering with glaucoma or OHT. [8][9][10][11][12][13][14][15][16][17][18][19] It is of importance to study such regimes specifically in glaucoma and OHT populations, as it is these patients who are most at risk of a raised IOP. 6,12,20 It has been suggested that this pressure rise may be transient postoperatively.…”

Section: Introductionmentioning

confidence: 99%

Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension?

Gupta

Vernon

2015

Eye

View full text Add to dashboard Cite

Purpose To determine whether the 1-day postoperative intraocular pressure (IOP) check following routine uncomplicated phacoemulsification is necessary in patients with pre-existing glaucoma and ocular hypertension (OHT), if acetazolamide prophylaxis is used. To investigate the practice of UK glaucoma specialists in IOP rise prophylaxis and follow-up regimes.Patients and methods The IOP 1-day postoperatively was analysed against the last recorded IOP before phacoemulsification in a cohort of patients with glaucoma or OHT who underwent uncomplicated phacoemulsification cataract surgery between December 2009 and September 2012, where it was routine practice to give acetazolamide postoperatively. UK and Eire Glaucoma Society members were surveyed via an online questionnaire to analyse practice among UK glaucoma specialists. Results One hundred and seven eyes were studied: 99 with glaucoma and 8 with OHT. The mean IOP change was À 0.8 mm Hg with only two eyes measuring 430 mm Hg postoperatively (2%). Both these eyes received 750 mg acetazolamide. Eighteen (17%) eyes had an IOP rise of at least 30%. In the survey of practice there were 65 respondents. Twenty-one (32%) respondents did not use IOP prophylaxis. Only 17 (26%) of respondents routinely reviewed their patients 1-day postoperatively.Conclusion Our prophylactic acetazolamide regime does not completely eliminate the risk of an IOP 430 mm Hg on day 1 post routine phacoemulsification in glaucoma/ OHT patients. Patients with pre-existing glaucoma, despite acetazolamide prophylaxis, will require IOP management decisions on the first postoperative day after uncomplicated phacoemulsification surgery. UK expert practice is non-uniform with regard to IOP prophylaxis, and the 1-day review, and further discussion and formulation of consensus appears necessary.

show abstract

Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat

Abstract: Brinzolamide, brimonidine, acetazolamide, intracameral acetylcholine, and timolol had similar effects in reducing IOP increases after phacoemulsification performed using Viscoat.

Cited by 22 publications

References 24 publications

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Comparison of Efficacy and Safety of Topical Dorzolamide-Timolol Maleate Combination with Oral Acetazolamide for Prevention of Intraocular Pressure Rise Following Phacoemulsification Surgery

Complications of cataract surgery

Is the 1-day postoperative IOP check needed post uncomplicated phacoemulsification in patients with glaucoma and ocular hypertension?

Contact Info

Product

Resources

About