Effect of Anxiety and Depression on the Recurrence of Paroxysmal Atrial Fibrillation After Circumferential Pulmonary Vein Ablation

Yu, Shengbo; Zhao, Qingyan; Wu, Pan; Qin, Mu; Huang, He; Cui, Hongying; Huang, Congxin

doi:10.1111/j.1540-8167.2012.02436.x

Cited by 34 publications

(41 citation statements)

References 48 publications

(68 reference statements)

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“…Although several possible mechanisms have been suggested, such as correlation with systemic inflammation and elevated sympathetic tone, the mechanisms behind this relationship remain unclear. Both anxiety and depression improved after RFA, which is in line with previous studies …”

Section: Discussionsupporting

confidence: 92%

Predictors of improvement in arrhythmia‐specific symptoms and health‐related quality of life after catheter ablation of atrial fibrillation

Barmano

Charitakis

Karlsson

et al. 2018

Clinical Cardiology

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Background The primary goal of radiofrequency ablation (RFA) of atrial fibrillation (AF) is to improve symptoms and health‐related quality of life (HRQoL). However, most studies have focused on predictors of AF recurrence rather than on predictors of improvement in symptoms and HRQoL. Hypothesis We sought to explore predictors of improvement in arrhythmia‐specific symptoms and HRQoL after RFA of AF, and to evaluate the effects on symptoms, HRQoL, anxiety, and depression. Methods We studied 192 patients undergoing their first RFA of AF. The Medical Outcomes Study 36‐Item Short‐Form Health Survey (SF‐36), arrhythmia‐specific questionnaire in tachycardia and arrhythmia (ASTA), and hospital anxiety and depression scale (HADS) questionnaires were filled out at baseline, at 4 months, and at a 1‐year follow‐up. Results All questionnaire scale scores improved significantly over time. In the ASTA symptom scale score, female gender and > 10 AF episodes the month before RFA were significant positive predictors of improvement, while diabetes and AF recurrence within 12 months after RFA were significant negative predictors (R2 = 0.18; P < 0.001). In the ASTA HRQoL scale score, the presence of heart failure and > 10 AF episodes the month before RFA were significant positive predictors of improvement, while diabetes, maximum left atrial volume and AF recurrence were significant negative predictors (R2 = 0.20; P < 0.001). Conclusion Left atrial volume, gender, diabetes, heart failure, the frequency of AF attacks prior to RFA, and recurrence of AF after RFA were significant factors affecting improvement in symptoms and HRQoL after RFA of AF. Future studies are warranted to confirm these findings.

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Section: Discussionsupporting

confidence: 92%

Predictors of improvement in arrhythmia‐specific symptoms and health‐related quality of life after catheter ablation of atrial fibrillation

Barmano

Charitakis

Karlsson

et al. 2018

Clinical Cardiology

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“…Treatment strategy was determined by participant and electrophysiologist preference . The same study also found participants with higher levels of anxiety and depression to have more AF recurrence at follow‐up after CPVA . A second study found greater improvement in depression, anxiety, and quality of life among 166 participants with paroxysmal AF using catheter ablation over antiarrhythmic drugs .…”

Section: Discussionmentioning

confidence: 90%

“…A recent study of 210 participants with paroxysmal AF found a reduction in anxiety and depression and an increase in quality of life following circumferential pulmonary vein isolation (CPVA) over AF treated with antiarrhythmic medications. Treatment strategy was determined by participant and electrophysiologist preference . The same study also found participants with higher levels of anxiety and depression to have more AF recurrence at follow‐up after CPVA .…”

Section: Discussionmentioning

confidence: 93%

The Effect of Anxiety and Depression on Symptoms Attributed to Atrial Fibrillation

Thompson

Barksdale

Sears

et al. 2013

Pacing Clinical Electrophis

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“…Mohanty et al and Yu et al both assessed improvement in depression and anxiety in patients undergoing catheter ablation [36, 37]. Mohanty et al reported that successful ablation had greater improvement in the Hospital Anxiety and depression scale and BDI scores, whereas the STAI scores did not show any association with ablation success [36].…”

Section: Resultsmentioning

confidence: 99%

“…Mohanty et al reported that successful ablation had greater improvement in the Hospital Anxiety and depression scale and BDI scores, whereas the STAI scores did not show any association with ablation success [36]. Yu et al also noted that depression and anxiety increases the recurrence risk of persistent AF after circumferential pulmonary vein ablation [37]. …”

Section: Resultsmentioning

confidence: 99%

A Systematic Review of Depression and Anxiety in Patients with Atrial Fibrillation: The Mind-Heart Link

Patel

Conkey

Sohaney

et al. 2013

Cardiovascular Psychiatry and Neurology

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Atrial fibrillation (AF) is the most commonly seen arrhythmia in clinical practice. At present, few studies have been conducted centering on depression and anxiety in AF patients. Our aim in this systematic review is to use the relevant literature to (1) describe the prevalence of depression and anxiety in AF patients, (2) assess the impact that depression and anxiety have on illness perception in patients with AF, (3) provide evidence to support a hypothetical connection between the pathophysiology of AF and depression and anxiety, (4) evaluate the benefit of treatment of AF on depression and anxiety, and (5) give insight on medically managing a patient with AF and concomitant depression and anxiety.

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Effect of Anxiety and Depression on the Recurrence of Paroxysmal Atrial Fibrillation After Circumferential Pulmonary Vein Ablation

Abstract: CPVA can ameliorate anxiety and depression, which may contribute to improvement of quality of life in patients with paroxysmal AF. Anxiety and depression increase the recurrence risk of AF after CPVA.

Cited by 34 publications

References 48 publications

Predictors of improvement in arrhythmia‐specific symptoms and health‐related quality of life after catheter ablation of atrial fibrillation

Predictors of improvement in arrhythmia‐specific symptoms and health‐related quality of life after catheter ablation of atrial fibrillation

The Effect of Anxiety and Depression on Symptoms Attributed to Atrial Fibrillation

A Systematic Review of Depression and Anxiety in Patients with Atrial Fibrillation: The Mind-Heart Link

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