2021
DOI: 10.1016/j.ijbiomac.2021.10.009
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Effect of bassorin (derived from gum tragacanth) and halloysite nanotubes on physicochemical properties and the osteoconductivity of methylcellulose-based injectable hydrogels

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Cited by 15 publications
(9 citation statements)
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“…For example, a study showed that nano-hydroxyapatite (n-HA)/glycol chitosan (G-CS)/hyaluronic acid (HyA) hydrogels were cytocompatible and nontoxic, with excellent potential for application in bone tissue engineering [ 2 ]. Another study with thermosensitive methylcellulose (MC) hydrogels containing bassorin (Ba) and halloysite nanotubes (HNTs) achieved excellent proliferation, differentiation, cellular mineralization, and bone cell-specific gene expression [ 3 ]. A study produced nanocomposite hydrogels of chitosan, modified halloysite nanotubes, and icariin, and found that the biocompatibility improved the in vivo bone formation and the differentiation of encapsulated cells [ 4 ].…”
Section: Introductionmentioning
confidence: 99%
“…For example, a study showed that nano-hydroxyapatite (n-HA)/glycol chitosan (G-CS)/hyaluronic acid (HyA) hydrogels were cytocompatible and nontoxic, with excellent potential for application in bone tissue engineering [ 2 ]. Another study with thermosensitive methylcellulose (MC) hydrogels containing bassorin (Ba) and halloysite nanotubes (HNTs) achieved excellent proliferation, differentiation, cellular mineralization, and bone cell-specific gene expression [ 3 ]. A study produced nanocomposite hydrogels of chitosan, modified halloysite nanotubes, and icariin, and found that the biocompatibility improved the in vivo bone formation and the differentiation of encapsulated cells [ 4 ].…”
Section: Introductionmentioning
confidence: 99%
“…This can be associated with a tighter network structure formed by Fs NPs and the hydrogen bond formation between the Fs NPs and the hydrogel network. 30,35 As can be observed from the figure, the PPF-MPEG hydrogels demonstrated lower swelling ratios at a lower concentration (4% w/v) than PPF-MPEG-6. As the polymer concentration decreases, fewer groups are available to form hydrogen bonds, which can explain the lower swelling ratio observed.…”
Section: Materials Advances Papermentioning
confidence: 72%
“…The compressive test was conducted in triplicate for each sample, and the compressive strength and compressive modulus were determined based on the stress–strain curve. 35,36…”
Section: Methodsmentioning
confidence: 99%
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“…The incorporation of BC or Cloisite Na + did not change the pore geometry considerably, yet consistent with the literature [31], the PCC with additives revealed a denser and more uniform microstructure compared with the particle-free samples. The average pore size decreased from 130 ± 40 μm for PCC3 to 28 ± 10 μm for PCC-B2 (Table 2), which could be due to its higher dry mass as well as its highly dense, robust, and well-developed network structures resulting in the creation of pores with smaller sizes [25,32]. Furthermore, no evidence of phase separation was observed in all PCCs, and the particles were distributed homogeneously in most PCCs.…”
Section: Morphological Propertiesmentioning
confidence: 97%