Effect of Biomimetic Deposition on Anodized Titanium Surfaces

Abstract

Surface energy and hydrophilicity of implant surfaces have been known to play an important role in subsequent cellular responses on the implant surface. The aim of the present study was to evaluate the effects of biomimetic deposition of anodized surfaces on surface wettability, surface energy, and osteoblast responses. Ti discs with 2 different surface topographies (machined and anodized) were immersed in Hanks' balanced salt solution (HBSS) and modified simulated body fluid (SBF) solution for 2 weeks at physiologic conditions of 37 °C, initial pH of 7.4, and p(CO(2)) of 0.05 atm. Scanning electron microscopic (SEM) observation and energy-dispersive spectroscopic (EDS) microanalysis showed the deposition of calcium phosphate (CaP) onto anodized Ti surfaces immersed in modified SBF. Surface energy, surface wettability, and osteoblast responses, including cell attachment capacity, cell proliferation rate, and cell differentiation level, significantly increased on anodized Ti surfaces immersed in modified SBF. The effects of biomimetic deposition with modified SBF on physiochemical surface characteristics and cell biological responses were greater on anodized surfaces than on machined surfaces. These results indicate that biomimetic deposition with effective SBF may enhance the interaction between anodized Ti surfaces and their biological environment, consequently improving bone healing of dental Ti implants.

Natural dyeing with anthocyanins from Hibiscus rosa sinensis flowers

“…It is thought that physiochemical modification by CaP precipitation may affect various osteoblast cell responses to treated surfaces immersed in modified simulated body fluids. The release of Ca 2+ and PO from the CaP precipitate increased the hydration of the Ti surface, achieving protein adsorption and subsequent cell responses 34. Surface treatment may enhance the interaction between implant and bone tissue in the biological environment, consequently promoting the bone tissue healing and osseointegration of dental implant treatment.…”

Research of StemBios Cell Therapy on Dental Implants Containing Nanostructured Surfaces

“…The release of Ca 2+ and PO 3− 4 from the CaP precipitate increased the hydration of the Ti surface, affecting protein adsorption and subsequent cell responses. 42 Surface treatment may enhance the interaction between implant and bone in a biological environment, consequently improving bone healing and osseointegration of an implant.…”

Stress effect on bone remodeling and osseointegration on dental implant with novel nano/microporous surface functionalization

“…The release of Ca 2þ and PO 4 3À from the CaP precipitate increased the hydration of the Ti surface, achieving protein adsorption and subsequent cell responses. 34 Surface treatment may enhance the interaction between implant and bone tissue in the biological environment, consequently promoting the bone tissue healing and osseointegration of dental implant treatment.…”