Effect of broad-spectrum biofilm inhibitor raffinose, a plant galactoside, on the inhibition of co-culture biofilm on the microfiltration membrane

Kim, Han Shin; Jang, Yongsun; Ham, So Young; Park, Jeong Hoon; Kang, Hye Won; Yun, Eun Tae; Shin, Dong Hwa; Kim, Kyoung Chul; Park, Hee Deung

doi:10.1016/j.jhazmat.2020.123501

Cited by 12 publications

(6 citation statements)

References 29 publications

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“…The result indicated that furanone C-30 only inhibits the P. aeruginosa biofilm while the raffinose inhibits the biofilm formation in both bacteria. These findings could be useful for the protection of membrane bioreactors from biofouling . Wolf and co-workers in 2017 reported the biochemical and structural features of Photorhabdus luminescens lectin (PllA), an orthologue of LecA encoded with the gene plu2096 , and screened various galactosides.…”

Section: Naturally Occurring Carbohydrate-based Antibiofilm Agents An...mentioning

confidence: 99%

“…These findings could be useful for the protection of membrane bioreactors from biofouling. 63 Wolf and co-workers in 2017 64 reported the biochemical and structural features of Photorhabdus luminescens lectin (PllA), an orthologue of LecA encoded with the gene plu2096, and screened various galactosides. PIIA showed a high binding affinity and high specificity for α-galactoside ligands.…”

Section: Naturally Occurring Carbohydrate-based Antibiofilm Agents An...mentioning

confidence: 99%

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Small Carbohydrate Derivatives as Potent Antibiofilm Agents

Singh

Kulkarni

2022

J. Med. Chem.

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Biofilm formation by most pathogenic bacteria is considered as one of the key mechanisms associated with virulence and antibiotic resistance. Biofilm-forming bacteria adhere to the surfaces of biological or implant medical devices and create communities within their self-produced extracellular matrix that are difficult to treat by existing antibiotics. There is an urgent need to synthesize and screen structurally diverse molecules for their antibiofilm activity that can remove or minimize the bacterial biofilm. The development of carbohydrate-based small molecules as antibiofilm agents holds a great promise in addressing the problem of the eradication of biofilm-related infections. Owing to their structural diversity and specificity, the sugar scaffolds are valuable entities for developing antibiofilm agents. In this perspective, we discuss the literature pertaining to carbohydrate-based natural antibiofilm agents and provide an overview of the design, activity, and mode of action of potent synthetic carbohydrate-based molecules.

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Section: Naturally Occurring Carbohydrate-based Antibiofilm Agents An...mentioning

confidence: 99%

Section: Naturally Occurring Carbohydrate-based Antibiofilm Agents An...mentioning

confidence: 99%

Small Carbohydrate Derivatives as Potent Antibiofilm Agents

Singh

Kulkarni

2022

J. Med. Chem.

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“…Bulk and non-nutritive sweeteners have been shown to reduce oral biofilm formation and activity by suppressing the expression of biofilm- and virulence-related genes ( Fig. 3 ) [ [26] , [27] , [28] , 87 ]. In addition, unlike sucrose, bulk and non-nutritive sweeteners cannot be utilized by S. mutans as a substrate for biofilm matrix synthesis, resulting in reduced biofilm formation [ 32 ].…”

Section: Role Of Sweeteners In Oral Biofilm Modulationmentioning

confidence: 99%

“…In addition, bulk sweeteners and non-nutritive sweeteners inhibit biofilm- and virulence-related gene expression, leading to a non-cariogenic biofilm with low levels of polysaccharide. Information obtained from the literature [ 6 , [26] , [27] , [28] , 32 , 87 ]. EPS, extracellular polymeric substances; Gtf, glucosyltransferase.…”

Section: Role Of Sweeteners In Oral Biofilm Modulationmentioning

confidence: 99%

Alteration of oral microbial biofilms by sweeteners

Jeong,

Khan,

Tabassum

et al. 2024

Biofilm

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“…Certain plant compounds, including flavonoids, alkaloids, terpenoids, phenols, and polyphenols, exhibit antibacterial and antibiofilm activities by inhibiting efflux through pump inhibition and disrupting bacterial quorum-sensing systems. For example, raffinose, which is commonly found in plants, significantly inhibits the formation of S. aureus biofilms [ 90 ]. Raffinose primarily inhibits the c-di-GMP mechanism of S. aureus , and it also inhibits bacterial biofilm formation by interfering with bacterial quorum sensing.…”

Section: Promising Strategies Against S Aureus Inf...mentioning

confidence: 99%

Staphylococcus aureus and biofilms: transmission, threats, and promising strategies in animal husbandry

Song,

Tang,

Ding

et al. 2024

J Animal Sci Biotechnol

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Staphylococcus aureus (S. aureus) is a common pathogenic bacterium in animal husbandry that can cause diseases such as mastitis, skin infections, arthritis, and other ailments. The formation of biofilms threatens and exacerbates S. aureus infection by allowing the bacteria to adhere to pathological areas and livestock product surfaces, thus triggering animal health crises and safety issues with livestock products. To solve this problem, in this review, we provide a brief overview of the harm caused by S. aureus and its biofilms on livestock and animal byproducts (meat and dairy products). We also describe the ways in which S. aureus spreads in animals and the threats it poses to the livestock industry. The processes and molecular mechanisms involved in biofilm formation are then explained. Finally, we discuss strategies for the removal and eradication of S. aureus and biofilms in animal husbandry, including the use of antimicrobial peptides, plant extracts, nanoparticles, phages, and antibodies. These strategies to reduce the spread of S. aureus in animal husbandry help maintain livestock health and improve productivity to ensure the ecologically sustainable development of animal husbandry and the safety of livestock products.

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Effect of broad-spectrum biofilm inhibitor raffinose, a plant galactoside, on the inhibition of co-culture biofilm on the microfiltration membrane

Cited by 12 publications

References 29 publications

Small Carbohydrate Derivatives as Potent Antibiofilm Agents

Small Carbohydrate Derivatives as Potent Antibiofilm Agents

Alteration of oral microbial biofilms by sweeteners

Staphylococcus aureus and biofilms: transmission, threats, and promising strategies in animal husbandry

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