Effect of cadmium accumulation on serum vitellogenin levels and hepatosomatic and gonadosomatic indices of winter flounder (Pleuronectes americanus)

Chronic toxicity of verapamil on juvenile rainbow trout (Oncorhynchus mykiss): Effects on morphological indices, hematological parameters and antioxidant responses

“…Other information as in Fig. 1. in HSI are normally associated with enhanced detoxification activities in response to the presence of toxic compounds [38][39][40]. In this study, significant lower CF and HSI were observed in the VRP treated group with the highest concentration (E3 group), indicating a decrease in fish growth and overall condition caused by direct metabolic effect on fish.…”

Cadmium Accumulation in Liver and Kidneys and Hepatic Metallothionein and Glutathione Levels in Rana ridibunda, After Exposure to CdCl2

“…Our findings are in agreement with those of KiriakopoulouSklavounou (1983). Groten et al (1994) found no differences on body weight gain and food consumption in rats fed with 90 ppm of Cd for 10 months, while Pereira et al (1993) found a negative correlation between the HSI and the Cd concentration of the liver in Pleuronectes americanus exposed to dissolved CdCl 2 in seawater. Cope et al (1994) found a reduction in body growth of Lepomis macrochirus exposed to sediment contaminated with Cd.…”

In vitro and in vivo studies of the endocrine disrupting potency of cadmium in roach (Rutilus rutilus) liver

“…An inhibiting effect of CdCl 2 on vitellogenesis has also been reported in female flounder (Platichthys flesus; Povlsen et al, 1990) and juvenile rainbow trout (Olsson et al, 1995;Valencia et al, 1998) injected with 0.2-2 mg kg À1 body weight of CdCl 2 associated to 2-10 mg kg À1 E2. Maturating female (i.e with vitellogenic ovaries) winter flounders (Pleuronectes americanus) and rainbow trout exposed via water to CdCl 2 alone (between 25 and 100 lg L À1 ) also had decreased VTG production (Pereira et al, 1993;Haux et al, 1988). Apart from the estrogenic effect reported by Thomas (1989), the in vivo studies are pointing to an anti-estrogenic effect of Cd.…”