Effect of calcium phosphate addition to fluoride containing dental varnishes on enamel demineralization

Shen, Peiyan; Bagheri, Rafat; Walker, G.; Yuan, Yue; Stanton, David P.; Reynolds, Coralie; Reynolds, EC

doi:10.1111/adj.12385

Cited by 68 publications

(79 citation statements)

References 29 publications

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“…On the other hand, some studies claim that the addition of Ca and P ions to a glass ionomer-based material increases their availability for binding to the released F ions. 21,22 This is in accordance with the concept that a high initial concentration of F is better for inhibiting the formation of new lesions, while lower initial concentration is most effective for remineralization and control of the progression of lesions. 23 In addition, we hypothesize that a resinmodified glass-ionomer with Ca used as coating material could be effective in the long term since it acts mainly in the subsurface of the lesion in adjacent area of the material as showed by CSH values ( Figure 4A), but further studies are needed to elucidate this.…”

Section: Discussionsupporting

confidence: 87%

Effect of a resin-modified glass-ionomer with calcium on enamel demineralization inhibition: an in vitro study

et al. 2019

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We assessed the effect of a new coating material based on resin-modified glass-ionomer with calcium (Ca) in inhibiting the demineralization of underlying and adjacent areas surrounding caries-like lesions in enamel. The measures used were surface hardness (SH) and cross-sectional hardness (CSH). Thirty-six bovine enamel specimens (3 × 6 × 2 mm) were randomly allocated into three groups (n = 12): No treatment (NT); resin-modified glass-ionomer with Ca (Clinpro XT Varnish, 3M ESPE) (CL), and fluoride varnish (Duraphat, Colgate) (DU). The specimens were subjected to alternated immersions in demineralizing (6 h) and remineralizing solutions (18 h) for 7 days. SH measurements were conducted at standard distances of 150, 300, and 450 µm from the treatment area. CSH evaluated the mean hardness profile over the depth of the enamel surface and at standard distances from the materials. The energy-dispersive X-ray spectroscopy analysis was conducted to evaluate the demineralization bands created on the sublayer by % of calcium (Ca), phosphorus (P), and fluoride (F). Ca/P weight ratio was also calculated. Based on SH and CSH measurements, there was no difference between groups at the distances 150 µm (p = 0.882), 300 µm (p = 0.995), and 450 µm (p = 0.998). Up to 50 µm depth (at 150 µm from the treatment area), CL showed better performance than DU ( p< 0.05). NT presented higher loss of Ca and P than CL and DU (p < 0.05). There was no significant difference in the % of F ion among the three groups. The new coating material was similar to F varnish in attenuating enamel demineralization.

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Section: Discussionsupporting

confidence: 87%

Effect of a resin-modified glass-ionomer with calcium on enamel demineralization inhibition: an in vitro study

et al. 2019

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“…While some authors have observed that after 24 hours Profluorid has released approximately 17% of its fluoride content (201.34 μmol/g) and Clinpro White Varnish has released 16% (175 .87 μmol/g) [27], others have found that after 24 hours the percentage of fluoride released by Clinpro White Varnish was 6% and 20% after 7 days [28]. Bolis et al .…”

Section: Discussionmentioning

confidence: 99%

Efficacy of fluoride varnishes for preventing enamel demineralization after interproximal enamel reduction. Qualitative and quantitative evaluation

et al. 2017

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ObjectivesTo evaluate quantitatively and qualitatively the changes produced to enamel after interproximal reduction and subjected to demineralization cycles, after applying a fluoride varnish (Profluorid) and a fluoride varnish containing tricalcium phosphate modified by fumaric acid (Clinpro White).Materials and methods138 interproximal dental surfaces were divided into six groups: 1) Intact enamel; 2) Intact enamel + demineralization cycles (DC); 3) Interproximal Reduction (IR); 4) IR + DC; 5) IR + Profluorid + DC; 6) IR + Clinpro White + DC. IR was performed with a 0.5 mm cylindrical diamond bur. The weight percentage of calcium (Ca), phosphorous (P) and fluoride (F) were quantified by energy-dispersive X-ray spectrometry (EDX). Samples were examined under scanning electron microscopy (SEM).ResultsThe weight percentage of Ca was significantly higher (p<0.05) in Groups 1, 2 and 5 than Groups 4 and 6. No significant differences were detected in the weight percentage of Ca between Group 3 and the other groups (p>0.05). The weight percentage of P was similar among all six groups (p>0.05). F was detected on 65% of Group 6 surfaces. SEM images of Groups 4 and 6 showed signs of demineralization, while Group 5 did not.ConclusionsProfluorid application acts as a barrier against the demineralization of interproximally reduced enamel.

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“…Studies are in progress to give an idea about the effects of these materials with derivatives of calcium phosphate on carious enamel lesions. A good results were concluded about the ability of these materials to protect enamel against the demineralization [22] .…”

Section: Fig (1)mentioning

confidence: 99%

Minimal invasive treatment of carious pits and fissures: preventive measures

El-Marakby¹

2017

IJDOH

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Effect of calcium phosphate addition to fluoride containing dental varnishes on enamel demineralization

Abstract: MI Varnish containing fluoride and CPP-ACP was superior to the other varnishes in protecting against enamel demineralization.

Cited by 68 publications

References 29 publications

Effect of a resin-modified glass-ionomer with calcium on enamel demineralization inhibition: an in vitro study

Effect of a resin-modified glass-ionomer with calcium on enamel demineralization inhibition: an in vitro study

Efficacy of fluoride varnishes for preventing enamel demineralization after interproximal enamel reduction. Qualitative and quantitative evaluation

Minimal invasive treatment of carious pits and fissures: preventive measures

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