Effect of cane use on bone marrow lesion volume in people with medial tibiofemoral knee osteoarthritis: randomized clinical trial

Ginckel, Ans Van; Hinman, Rana S; Wrigley, Tim V.; Hunter, David J.; Marshall, Caroline; Duryea, J.; Melo, Luciano; Simić, Milena; Kasza, Jessica; Robbins, Sarah R; Wallis, Jason; Bennell, Kim L

doi:10.1016/j.joca.2019.05.004

Cited by 17 publications

(4 citation statements)

References 47 publications

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“…An RCT in 79 participants with medial femorotibial OA found no difference in total medial BML per unit bone volume change by MRI between those randomized to daily cane use over 3 months vs controls 74 .…”

Section: Mechanical and Surgical Interventionmentioning

confidence: 99%

Osteoarthritis year in review 2020: imaging

Eckstein

Wirth

Culvenor

2021

Osteoarthritis and Cartilage

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Section: Mechanical and Surgical Interventionmentioning

confidence: 99%

Osteoarthritis year in review 2020: imaging

Eckstein

Wirth

Culvenor

2021

Osteoarthritis and Cartilage

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“…Ежедневное использование трости во время ходьбы в течение 3 месяцев у 79 больных с медиальным тибиофеморальным ОА с целью снижения нагрузки на коленный сустав не изменило объёмы ОКМ по сравнению с пациентами, не использующими трость [43]. Метаанализ, проведённый с целью оценки влияния длительной лечебной физкультуры (более 6 месяцев) на состояние суставных структур у пациентов с ОА коленного сустава не обнаружил какой-либо динамики рентгенологической картины, морфологии хрящей, синовита и суставного выпота, но выявил вероятность незначительного нарастание ОКМ в бедренной и большеберцовой кости [44].…”

Section: влияние физической нагрузки на окм при остеоартритеunclassified

Bone marrow edema in osteoarthritis of the knee joint

Noskov,

Snigireva,

Parulya

et al. 2024

PoMPh

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The term "bone marrow edema" (BME) in MRI examination of the knee joint is used to describe areas of decreased signal intensity on T1-weighted images or increased signal intensity on T2-weighted images in the subchondral bone. BME is classified into ischemic (osteonecrosis), mechanical (trauma), and reactive (arthritis) types. In this review, the causes and differences in BME with spontaneous and secondary osteonecrosis and other characteristics of BME transitioning to a syndrome are considered. BME with injuries and bruises is usually reversible and passes after approximately 2–4 months, if accompanied by a cortical fracture, after 6–12 months. A fatigue fracture develops as a result of repeated overloading of normal bone structures, whereas fractures in zones of subchondral bone insufficiency spontaneously occur in pathologically changed bone tissues (for example, osteoporotic bones) without any trauma or overloading. Histological examination of the damaged subchondral bone in ischemic and mechanical BME revealed hemorrhages, microdestruction of bone trabeculae and vascular anomalies, and almost complete absence of direct edema in MRI-positive zones due to increased extracellular fluid content, which can be partially explained by methodological difficulties in detecting increased extracellular fluid by histopathological methods. Prostacyclin and bisphosphonate have been proposed as conservative therapies for ischemic and mechanical BME.In osteoarthritis (OA) of the knee joints, BME is considered a marker of rapid progression. Data on the influence of obesity, therapeutic exercise and diet, and the use of a cane on BME are presented. Analysis of the effectiveness of conservative therapy revealed a weakly positive response to bisphosphonates. Inhibitors of nerve growth factor (NGF) — monoclonal antibodies to nerve growth factor (like tanezumab and fulranumab) — reduced the severity of pain but led to an increase in the frequency of osteonecrosis and endoprosthesis. Two studies have shown a decrease in the intensity of BME with oral chondroitin sulfate. The attention of orthopedists is focused on subchondroplasty using calcium phosphates. Subchondral filling, which strengthens the bone and replaces the lost barrier function of cartilage, has a symptomatic effect and effectively counteracts the development of BME, although the long-term results need to be studied.

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“…The primary outcome was NRS, [16] which is a numeric scale for the objective assessment of pain, which is a subjective sensation felt by individual patients, with 0 representing "no pain" and 10 representing "the worst pain imaginable. "…”

Section: Outcome Measuresmentioning

confidence: 99%

Integrative Korean medicine treatment for inpatients with osteoarthritis of the knee: An observational study

Lee,

Oh,

Bae

et al. 2024

Medicine

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The use of integrative Korean medicine treatment (IKMT) for patients with knee osteoarthritis (OA) has been reported previously; however, to date, no studies have investigated the long-term prognosis of these patients following IKMT for primary knee OA. We aimed to examine the long-term effects of IKMT in patients diagnosed with primary knee OA and receiving IKMT during hospitalization. This retrospective observational study, complemented by a follow-up survey, included patients with primary knee OA who received IKMT during hospitalization across 7 Korean medicine hospitals. The primary outcome was the Numerical Rating Scale knee-pain score, whereas the secondary outcomes were the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), EuroQol-5 dimension-5 level questionnaire (EQ-5D-5L), and Patient Global Impression of Change scores. Patients were evaluated at admission, discharge, and during follow-up. Of the 180 included patients, 81 responded to the survey. Compared with the corresponding values at admission, the Numerical Rating Scale score decreased by 2.44 (2.08–2.81) points at discharge and 1.89 (1.5–2.26) points at follow-up. Additionally, compared with their scores at admission, the WOMAC score decreased by 17.20 (13.68–20.71) points at discharge and 25.74 (22.22–29.26) points at follow-up, whereas the EuroQol-5 dimension-5 level questionnaire score improved by ‐0.15 (‐0.18 to ‐0.12) points at discharge and ‐0.12 (‐0.15 to ‐0.09) points at follow-up. The patients expressed high satisfaction with pharmacopuncture (65.4%), acupuncture (54.03%), physical therapy (35.8%), and herbal medicine (34.6%). Regarding Patient Global Impression of Change, 96.30% of the patients reported improvement. IKMT was effective in improving pain, functional disability, and quality of life in patients with primary knee OA. Its effects were maintained throughout the long-term follow-up period, and physical functions continuously improved.

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Effect of cane use on bone marrow lesion volume in people with medial tibiofemoral knee osteoarthritis: randomized clinical trial

Cited by 17 publications

References 47 publications

Osteoarthritis year in review 2020: imaging

Osteoarthritis year in review 2020: imaging

Bone marrow edema in osteoarthritis of the knee joint

Integrative Korean medicine treatment for inpatients with osteoarthritis of the knee: An observational study

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