Effect of cinnamomum zeylanicum blume essential oil on the rowth and morphogenesis of some potentially pathogenic Aspergillus species

Abstract

Cinnamomum zeylanicum Blume is known for a wide range of medicinal properties. This study aimed to assess the interference of C. zeylanicum essential oil on the growth and morphogenesis of some potentially pathogenic Aspergillus species. The essential oil presented strong antifungal effect causing the growth inhibition of the assayed strains and development of large growth inhibition zones. MIC50 and MIC90 values were 40 and 80 µL/mL, respectively. 80, 40 and 20 µL/mL of the oil strongly inhibited the radial mycelial growth of A. niger, A. flavus and A. fumigatus along 14 days. 80 and 40 µL/mL of the oil caused a 100% inhibition of the fungal spore germination. Main morphological changes observed under light microscopy provided by the essential oil in the fungal strains were decreased conidiation, leakage of cytoplasm, loss of pigmentation and disrupted cell structure indicating fungal wall degeneration. It is concluded that C. zeylanicum essential oil could be known as potential antifungal compound, particularly, to protect against the growth of Aspergillus species.

Growth Inhibition of Aspergillus Ochraceus ZMPBF 318 and Penicillium Expansum ZMPBF 565 by Four Essential Oils

“…These results are consistent with studies of the effect of cinnamon oil on the growth of Aspergillus ochraceus (6,7). High concentrations of cinnamon seem to inhibit the development of asexual spores and cause signifi cant morphological changes in the mycelium of the Aspergillus genera (6).…”

“…Many essential oils and their ingredients possess antibacterial, antifungal, and antiviral properties (5)(6)(7)(8)(9)(10)(11)(12)(13). These include cassia, cinnamon, clove, garlic, sage, oregano, pimento, thyme, rosemary, scutellaria, and other (14).…”

The Effects Of Wild Thyme (Thymus Serpyllum L.) Essential Oil Components Against Ochratoxin-Producing Aspergilli / Majčina Dušica (Thymus Serpyllum L.) I Njezine Komponente Protiv Okratoksikotvornih Vrsta Aspergillusa

“…The mechanism of antioxidantive action regarding the inhibition of mycelial growth of toxigenic fungi is not clear. Many studies have described antioxidative effects of antifungal compounds, their relation to protoplasmic poisoning, disruption of microbial cell wall, and precipitation of cell proteins (10,15). The activity of these compounds has been attributed to the presence of an aromatic nucleus and an OH group which are known to form hydrogen bonds within active sites of enzymes (10,16,17).…”

Paracetamol induced hepatic toxicity and amelioration by cinnamon in rats

“…In addition to its culinary uses, cinnamon has been used in traditional herbal medicine to treat different health conditions (Gruenwald et al, 2010). Some studies showed that cinnamon extracts and its constituents also effective in the treatment of cancer (Nishida et al, 2003), insecticidal (Yang et al 2005), hypotensive (Preuss et al, 2006), antioxidant and antimutagenic activities (Jayaprakasha et al, 2007), cholesterol-lowering effects (Subash Babu et al, 2007), antimicrobial action (Carmo et al, 2008) and anti-inflammatory effect (Tung et al, 2008). The liver is the largest internal organ in the body and played a very important role in the detoxification of harmful and toxic substances.…”