Effect of Combining Immersion Therapy with Shengji Ointment on Wound Healing Rate and Adverse Reaction Rate in Patients with Second-Degree Burn

Abstract

Objective. To explore the effect of combining immersion therapy with Shengji ointment on wound healing rate and adverse reaction rate (ARR) in patients with second-degree burn. Methods. The data of 80 patients with second-degree burn treated in our hospital from February 2019 to February 2020 were retrospectively analyzed by the means of retrospective study, and the patients were equally divided into the treatment group and the control group according to their admission order, with 40 cases each. Immersion therapy was performed to all patients (7 d); after that, patients in the control group received routine medication (7 d), and those in the treatment group were treated with Shengji ointment until the wounds were healed, so as to compare their wound healing condition, ARRs, levels of inflammatory factors, and infection incidence. Results. Compared with the control group after treatment, the treatment group presented significantly shorter wound healing time (12.14 ± 1.26 vs. 15.98 ± 1.20, P < 0.001), better wound healing rate and quality ( P < 0.05), and lower levels of inflammatory factors ( P < 0.001); no significant between-group difference in ARRs was shown ( P > 0.05); 34 patients in the treatment group (85.0%) and 26 patients in the control group (65.0%) had no infections, so the incidence rate of infections was significantly lower in the treatment group than in the control group (P < 0.05). Conclusion. Combining immersion therapy with Shengji ointment can reduce the levels of inflammatory factors in patients with second-degree burn, lower the incidence rate of infections, provide the conditions for wound healing, and increase the wound healing rate, which shall be promoted and applied in practice.

Effect of Chinese herbal topical medicine, acupuncture, and moxibustion on pressure ulcer wound healing: A meta‐analysis

“…A total of 1010 distinctive studies were found, of which 13 studies (between 2008 and 2022) satisfied the inclusion criteria and were comprised in the study. [25][26][27][28][29][30][31][32][33][34][35][36][37] This metaanalysis study based on 13 studies included 1073 subjects with pressure ulcer wound at the start of the study; 593 of them were using traditional Chinese medicine treatments, and 480 were control for pressure ulcer wounds. All studies evaluated the effect of Chinese herbal topical medicine, acupuncture, and moxibustion on pressure ulcer wound healing.…”

“…This meta-analysis study based on 13 studies included 1073 subjects with pressure ulcer wound at the start of the study; 593 of them were using traditional Chinese medicine treatments, and 480 were control for pressure ulcer wounds. [25][26][27][28][29][30][31][32][33][34][35][36][37] Traditional Chinese medicine treatments had significantly higher complete healing, and curative ratio post-treatment compared with control for subjects with pressure ulcer wounds. However, the analysis of outcomes should be performed with consideration because of the low number of selected studies and the low sample size of most of the selected studies found for the meta-analysis, 10 out of 13 studies with ≤100 subjects as sample size; recommending the need for other studies to confirm these findings or perhaps to significantly impact confidence in the influence evaluation.…”

“…Chinese herbal topical medicine is an oil-based ointment enclosing sesame oil, honey, and other small quantities of plant ingredients. [25][26][27][28][29][30][31][32][33][34][35][36][37] Numerous studies showed that Chinese herbal topical medicine endorses epithelial repair, inhibits bacterial growth, soothes wounds, retains moisture, relieves pain from wound surface, offers the best physiological environment for healing, and outcomes in progress for scar creation. [25][26][27][28][29][30][31][32][33][34][35][36][37] Acupuncture is founded on the system of meridians.…”

Microbial community succession in the intestine of mice with deep partial-thickness burns

“…Microbial phenotype analysis revealed that many anaerobes were significantly decreased due to burn injury but showed recovery in the late time after burn, potentially providing insight into the microbial succession associated with burn injury (Lovell et al, 2022). Burn injury can be divided into four types: first-degree burn, superficial second-degree burn, deep partial-thickness burn, and thirddegree burn (Guo and Yu, 2021). Deep partial-thickness burn wounds are characterized by blisters that extend into the reticular dermal layer and have a higher risk of chronic inflammation of the dermis (Lukiswanto et al, 2019), which can lead to infection or scarring.…”

“…Burn injury can be divided into four types: first-degree burn, superficial second-degree burn, deep partial-thickness burn, and third-degree burn ( Guo and Yu, 2021 ). Deep partial-thickness burn wounds are characterized by blisters that extend into the reticular dermal layer and have a higher risk of chronic inflammation of the dermis ( Lukiswanto et al, 2019 ), which can lead to infection or scarring.…”