Effect of continuous positive airway pressure on nocturnal urine production in patients with obstructive sleep apnea syndrome

Miyazato, Minoru; Tohyama, Kazuyo; Touyama, Masato; Nakamura, Hiroshi; Oshiro, Takeshi; Ueda, Shinichiro; Saitoh, Sei–Ichi

doi:10.1002/nau.22936

Cited by 47 publications

(40 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…22 Correspondingly, treatment of OSA with continuous positive airway pressure (CPAP) has been shown to reduce nocturia. 23 OSA has also been linked to other OAB symptoms such as urgency. 4,5,24 This suggests that the urological effects of OSA may extend beyond nocturnal polyuria, involving such mechanisms as OSA-induced hypoxia.…”

Section: Discussionmentioning

confidence: 99%

Sleep Disturbance and Fatigue Are Associated With More Severe Urinary Incontinence and Overactive Bladder Symptoms

Vetter

Lai

2017

Urology

View full text Add to dashboard Cite

Objective To investigate the relationship between sleep disturbance, fatigue, and urinary incontinence (UI)/overactive bladder (OAB) symptoms among patients with OAB. Methods Patients who were diagnosed with overactive bladder (OAB) and age-matched control subjects without OAB were enrolled. Sleep disturbance and fatigue symptoms were assessed using the PROMIS short forms. UI/OAB symptoms were assessed using the ICIQ-UI, ICIQ-OAB, OAB-q, UDI-6, and IIQ-7 questionnaires. Psychosocial health (depression, anxiety, perceived stress level) was also assessed. Results OAB patients reported significantly greater sleep disturbance compared to controls (PROMIS 8b T-scores: 54.3 ± 10.3 vs. 43.8 ± 9.2). OAB patients also reported significantly greater fatigue compared to controls (PROMIS 7a T-scores: 54.7 ± 9.6 vs. 46.0 ± 6.4). After adjusting for nocturia, the differences in sleep disturbance between OAB and controls became insignificant (p=0.21) while the differences in fatigue between OAB and controls remained significant (p=0.014). Among OAB patients, there were positive correlations between sleep disturbance and the severity of OAB symptoms (ICIQ-OAB), poorer health-related quality of life (OAB-q QOL), the severity of urinary incontinence symptoms (ICIQ-UI), greater incontinence impact (IIQ-7) and urinary bother (UDI-6). Positive correlations were also observed between fatigue and worse UI/OAB symptoms and quality of life. Both sleep disturbance and fatigue were associated with poor psychosocial health (depression, anxiety, higher stress level) among OAB patients. Conclusions Sleep disturbance and fatigue are present in substantial percentages of OAB patients. Among OAB patients, sleep disturbance and fatigue were associated with more severe UI/OAB symptoms, worse health-related quality of life, and poorer psychosocial health.

show abstract

Section: Discussionmentioning

confidence: 99%

Sleep Disturbance and Fatigue Are Associated With More Severe Urinary Incontinence and Overactive Bladder Symptoms

Vetter

Lai

2017

Urology

View full text Add to dashboard Cite

show abstract

“…Symptoms of nocturia in patients with OSAS may be associated with excessive urine production and hormonal imbalance during the night time. Some studies have demonstrated that continuous positive airway pressure can improve nocturia symptoms in patients with obstructive sleep apnea syndrome …”

Section: Introductionmentioning

confidence: 99%

“…Some studies have demonstrated that continuous positive airway pressure can improve nocturia symptoms in patients with obstructive sleep apnea syndrome. 14,15 The first-line pharmacotherapy for OAB starts with antimuscarinics or mirabegron. 16,17 These oral therapies are not sufficiently effective for many patients.…”

Section: Introductionmentioning

confidence: 99%

Can botox improve night‐time overactive bladder symptoms in women?

Miotła

Cartwright

Futyma

et al. 2016

Neurourology and Urodynamics

View full text Add to dashboard Cite

show abstract

“…ANP increases renal sodium and water excretion. Nighttime awakenings and subsequent trips to the bathroom can thus be reduced by applying continuous positive airway pressure (CPAP) …”

Section: Nocturnal Polyuriamentioning

confidence: 99%

“…Nighttime awakenings and subsequent trips to the bathroom can thus be reduced by applying continuous positive airway pressure (CPAP). [22][23][24][25] In patients with excessive fluid intake at night, nocturia can be improved by reducing fluid intake 4-6 hours prior to bedtime and limiting consumption of caffeinated products during the evening. 18 In patients with lower extremity oedema secondary to CHF or poor peripheral circulation, stockings and leg elevation may help to reduce the need to void during sleep.…”

Section: Noc Turnal P Oly Uriamentioning

confidence: 99%

Current guidelines and treatment paradigms for nocturnal polyuria: A “NEW” disease state forUSphysicians, patients and payers

Flores

Weiss

2019

Int J Clin Pract

View full text Add to dashboard Cite

Nocturia is one of the most bothersome symptoms encountered in urology, and its prevalence rises with age. Causes include both urological and non‐urological aetiologies, often in combination. The effects of nocturia on a patient's quality of life can be detrimental. The initial approach to managing this condition includes appropriately classifying nocturia based on the results of a 24‐hour bladder diary. Broadly, the categories under which nocturia can be classified include: low nocturnal or global bladder capacity, nocturnal polyuria, global polyuria and mixed.Based on the type of nocturia and possible underlying causes, clinicians can appropriately discuss with patients the treatment plans that may include a combination of behavioural, pharmacologic, and invasive therapy. The available literature on the management of nocturia was reviewed. Findings were incorporated into a practice‐based approach for its workup and treatment.

show abstract

Effect of continuous positive airway pressure on nocturnal urine production in patients with obstructive sleep apnea syndrome

Abstract: CPAP treatment decreases night-time urinary frequency by reducing nocturnal urine production and improves QOL in patients with OSAS. Neurourol. Urodynam. 36:376-379, 2017. © 2015 Wiley Periodicals, Inc.

Cited by 47 publications

References 35 publications

Sleep Disturbance and Fatigue Are Associated With More Severe Urinary Incontinence and Overactive Bladder Symptoms

Sleep Disturbance and Fatigue Are Associated With More Severe Urinary Incontinence and Overactive Bladder Symptoms

Can botox improve night‐time overactive bladder symptoms in women?

Current guidelines and treatment paradigms for nocturnal polyuria: A “NEW” disease state forUSphysicians, patients and payers

Contact Info

Product

Resources

About