Effect of Curcumin on Serum and Liver Cholesterol Levels in the Rat

Rao, D. Subba; Sekhara, N C; Satyanarayana, M. N.; Srinivasan, Malathi

doi:10.1093/jn/100.11.1307

Cited by 194 publications

(95 citation statements)

References 19 publications

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“…The reduced cholesterol levels in turmeric-treated animals is a clear indication of stimulated bile fluid secretion as well as biliary cholesterol secretion and enhanced excretion of bile acids and cholesterol in feces which is almost similar to the report published by many authors (Rao et al, 1970;Patil and Srinivasan, 1971;Keshavarz, 1976;Soudamini et al, 1992;Soni et al, 1992;Hussain and Chandrasekhara, 1992;Hussain and Chandrasekhara, 1994).…”

Section: Discussionsupporting

confidence: 87%

Effects of turmeric and garlic on blood cholesterol level

Chowdhury

Moinuddin

Islam

2008

Bangladesh J Pharmacol

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Section: Discussionsupporting

confidence: 87%

Effects of turmeric and garlic on blood cholesterol level

Chowdhury

Moinuddin

Islam

2008

Bangladesh J Pharmacol

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“…Previous studies have indicated that curcumin and an ether extract of turmeric have hypolipaemic action in rats (Rao et al, 1970) and lower cholesterol, fatty acids and triglycerides in alcohol induced toxicity (Rukkumani et al, 2003). Also, Ahmad-Raus et al (2001) reported that Curcuma domestica had a lowering effect on triglyceride level in the serum of high cholesterol diet animals but showed no effect on serum cholesterol and phospholipid levels.…”

Section: Discussionmentioning

confidence: 98%

Effect of turmeric powder on performance, carcass traits, humoral immune responses, and serum metabolites in broiler chickens

Nouzarian

Tabeidian²,

Toghyani³

et al. 2011

J. Anim. Feed Sci.

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The study was conducted to investigate the effect of dietary supplementation with turmeric powder as a natural growth promoter on performance, carcass traits, humoral immune responses and serum biochemical parameters in male broiler chickens. A total of 300 one-day-old male broiler chicks (Ross 308) were allocated to four treatments with five replicates. The dietary treatments consisted of the basal diet as control, 3.3, 6.6 and 10 g/kg turmeric powder added to the basal diet. The curcumin content of the turmeric powder was 1.16±0.03% by weight. Body weight gain and daily feed intake of chickens at different periods were not influenced by the dietary treatments. Broilers fed turmeric supplemented diets exhibited better feed efficiency over the grower and entire experimental periods in comparison with control group (P<0.05). A significant decrease (P<0.05) in abdominal fat pad and liver relative weight was observed in chickens fed the supplemented diets. Inclusion of turmeric powder also caused a marked (P<0.05) reduction in serum triglyceride concentration but no significant impact of turmeric powder was observed on antibody titer production against Newcastle and influenza viruses. The obtained results suggested that dietary inclusion of turmeric powder failed to induce any significant improvement on performance indexes except feed efficiency of broiler chickens. Nevertheless application of turmeric powder in the diet proved to have positive influence on carcass abdominal fat and serum triglyceride concentration at slaughter age.

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“…Curcumin is an orange-yellow crystalline powder obtained by solvent extraction of ground rhizomes of turmeric and purifi cation of extract is done by crystallization. The curcumin is an oilsoluble pigment having a melting point of 174°C (Rao et al 1970). It is stable at acidic pH but readily decomposes at pH above neutral.…”

Section: Introductionmentioning

confidence: 99%

Effect of extraction parameters on curcumin yield from turmeric

et al. 2010

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Effect of 4 independent variables -temperature (50-90°C), particle size (0.42-0.85 mm), mixing time (10-50 min) and solvent (ethanol) to meal ratio (10-50) on curcumin yield from turmeric (Curcuma longa L) was studied using central composite rotatable design. The experimental value of curcumin yield ranged between 4.49 and 12.89%. The second order model obtained for curcumin yield revealed a coeffi cient of determination (R 2 ) of 0.78 and standard error of 0.72. The linear, square and interaction terms were signifi cant at p <0.05 while lack of fi t was non-signifi cant at p >0.05. Surface graphs were plotted to optimize the curcumin extraction. The maximum curcumin yield was obtained when temperature, particle size, mixing time and solvent to meal ratio were 60°C, 0.42 mm, 30 min and 50, respectively.

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Effect of Curcumin on Serum and Liver Cholesterol Levels in the Rat

Cited by 194 publications

References 19 publications

Effects of turmeric and garlic on blood cholesterol level

Effects of turmeric and garlic on blood cholesterol level

Effect of turmeric powder on performance, carcass traits, humoral immune responses, and serum metabolites in broiler chickens

Effect of extraction parameters on curcumin yield from turmeric

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