Effect of cyclosporine on blood pressure

Nebivolol Effects on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients

“…12,13,21,22,31,40,43 The uniform use of tacrolimus rather than the more prohypertensive CNI, cyclosporine, may have also contributed to the excellent BP achieved in this population of kidney transplant recipients. 3,17,21,31,44,45 Our analysis did not show a difference in the effect of nebivolol and metoprolol on the renal function of kidney transplant recipients from baseline to the 12th month of the study. This is consistent with the relatively neutral physiologic effect of b-blockers on overall renal function.…”

Pharmacokinetic Drug-Drug Interaction of Calcium Channel Blockers With Cyclosporine in Hematopoietic Stem Cell Transplant Children

“…21 Thus, treating hypertension with a drug that increases CsA blood levels may consequently enhance hypertension and would thus not be suitable. 1 The identification of the safest CCB regarding potential drug-drug interactions with CsA is desirable in HSCT children.…”

Clinical evaluation of chronic nephrotoxicity of long‐term cyclosporine A treatment in adult patients with steroid‐dependent nephrotic syndrome

“…A recent systematic review regarding the effect of CsA on BP has shown an average increase of 5 mmHg with lower doses (1-4 mg/kg per day) of CsA, while the duration of the study was 2 years or less. 25 The course of hypertension is unclear in patients receiving long-term CsA treatment. Careful monitoring of BP is necessary in these patients.…”