Growing research interest in the use of diatomaceous biosilica results from its unique properties such as chemical inertness, biocompatibility, high mechanical and thermal stability, low thermal conductivity, and homogeneous porous structure with a large specific surface. Unlike the production of synthetic silica materials with a micro‐ or nanoscale structure in an expensive conventional manufacturing process, diatomaceous biosilica can be produced in huge quantities without significant expenditure of energy and materials. This fact makes it an unlimited, easily accessible, natural, inexpensive, and renewable material. Moreover, the production of biosilica is extremely environmental friendly, as there is essentially no toxic waste and the process does not require more energy compared to the production of synthetic silica‐based materials. For all these reasons, diatoms are an intriguing alternative to synthetic materials in developing cheap biomaterials used in a different branches of industry. In this review, the state‐of‐art of biosilica materials, their characteristics approaches, and possible ways of application have been reported.