2014
DOI: 10.1186/1471-2431-14-206
|View full text |Cite
|
Sign up to set email alerts
|

Effect of different assumptions for brain water content on absolute measures of cerebral oxygenation determined by frequency-domain near-infrared spectroscopy in preterm infants: an observational study

Abstract: BackgroundBrain-water content (BWC) decreases with maturation of the brain and potentially affects parameters of cerebral oxygenation determined by near-infrared spectroscopy (NIRS). Most commercially available devices do not take these maturational changes into account. The aim of this study was to determine the effect of different assumptions for BWC on parameters of cerebral oxygenation in preterm infants.MethodsConcentrations of oxy-, deoxy- and total hemoglobin and regional cerebral oxygen saturation (rcS… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
15
1

Year Published

2015
2015
2022
2022

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 19 publications
(16 citation statements)
references
References 16 publications
0
15
1
Order By: Relevance
“…A recent study reported that the variation of water content between infants leads to an uncertainty of StO 2 readings of up to 8% [51], which is also supported by [27,29]. This may systematically flaw clinical decisions.…”
Section: Implications Of C Thb and Background Absorbersmentioning
confidence: 93%
“…A recent study reported that the variation of water content between infants leads to an uncertainty of StO 2 readings of up to 8% [51], which is also supported by [27,29]. This may systematically flaw clinical decisions.…”
Section: Implications Of C Thb and Background Absorbersmentioning
confidence: 93%
“…In this spectral window, the Beer-Lambert law can be used to describe optical absorption in terms of principal chromophores: HbR, HbO, and water concentrations (µMol/l) [49]. Assuming a fixed 85% of water in brain tissue [51], HbO and HbR are evaluated by fitting the absorption spectra with extinction coefficients from literature [52]. Absolute value of cerebral SO 2 (%) is derived by the ratio between HbO and total hemoglobin (HbT ) while CBV (ml/100g) is proportional to HbT and calculated such as in prior studies [37,53].…”
Section: Discussionmentioning
confidence: 99%
“…Demel et al 27 showed that the absolute water (H2O) content of brain tissue affected determination of tissue oxygenation. We include H2O as a new chromophore in our analyses to evaluate wavelength selection in the BLL using…”
Section: Limitation Of Researchmentioning
confidence: 99%
“…For assessing the effects of H2O on the determination of StO2, the method of Demel et al27 could be a better alternative.All the analyses in this research are based on hyperspectral data from one palm. Because different people may have varying concentration of melanin and haemoglobin on their palms, the results obtained in this research could vary if more palm samples are used.…”
mentioning
confidence: 99%