Effect of different chewing gums on dental plaque pH, salivary pH, and buffering capacity in children: A randomized controlled trial

Muralikrishnan, Kameshwaran; Asokan, Sharath; Priya, P R Geetha

doi:10.4103/srmjrds.srmjrds_45_18

Cited by 5 publications

(9 citation statements)

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“…from using toothpaste when compared to the immediate salivary pH in the same group. This agrees with a previously reported researches (Muralikrishnan, Asokan, and Priya 2018). The xylitol mode of action includes absence of significant degradation into acidic endproducts by dental plaque, stimulation of salivary flow and increased buffering capacity, inhibition of plaque accumulation and of cariogenic bacteria (da Camara et al 2014).…”

Section: 3stability Of Preparationssupporting

confidence: 92%

A Comparative study of the Clinical and Microbiological Effects of Fluoride, Xylitol and Combined Fluoride-Xylitol Toothpastes in Children

Hamad

Hazem

Mahfouz

et al. 2021

Records of Pharmaceutical and Biomedical Sciences

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The aim of our study was to evaluate and compare the clinical and microbiological efficiency of Fluoride, Xylitol and combined Fluoride -Xylitol toothpastes on some salivary parameters in children by measuring salivary pH, salivary flow rate, salivary Streptococcus mutans (S. mutans) and Lactobacillus counts. Toothpastes were prepared by mortar and pestle technique. They were then evaluated for physicochemical properties like pH, cleanability, physical appearance, spreadability, abrasiveness, foaming power, homogeneity, content of moisture and volatile substances, and drug content. Twenty one normal apparently healthy children were selected from the Outpatient Dental Clinic of Pedodontic Department, Faculty of Dentistry, Suez Canal University. Children were randomly divided into three groups: children who brushed their teeth with fluoride toothpaste, children who brushed their teeth with xylitol toothpaste and children who brushed their teeth with combined fluoride xylitol toothpaste. Salivary samples were obtained from all groups and examined for salivary parameter changes (flow rate, pH) and microbiological assessment for (S. mutans and Lactobacilli) was done. All data were collected, tabled and statistically analyzed. Statistical significance was measured using p value. Xylitol was superior in increasing salivary flow rate and decreasing mean of S. mutans when compared to fluoride while Fluoride was superior in decreasing mean of Lactobacilli when compared to xylitol. Both had the same effect on increasing salivary pH.

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Section: 3stability Of Preparationssupporting

confidence: 92%

A Comparative study of the Clinical and Microbiological Effects of Fluoride, Xylitol and Combined Fluoride-Xylitol Toothpastes in Children

Hamad

Hazem

Mahfouz

et al. 2021

Records of Pharmaceutical and Biomedical Sciences

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“…The salivary pH in the saliva of the children was determined according to Kuriakose S et al (2013) using Indikrom pH strips, as pH is an main risk factor for the development of dental caries (21) According to Kameshwaran Muralikrishnan et al (2018). (22) The current study compared the effectiveness of Varnishes in the reduction of the Candida albicans count and changes in pH before and after application of Varnishes. It should also be noted that the effect of fluoride varnishes lasts for a specific period of time as it is a surface acting agent which shows its effect when in contact the susceptible tooth surface, inorder to prevent the incidence of dental caries.…”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

JR¹,

Gupta²,

Gambhir³

et al. 2022

Journal of Pharmaceutical Negative Results

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PURPOSE: Candida albicans one of the commensal organisms in the oral cavity, causes fermentation of the dietary carbohydrates leading to the formation of organic acids, which contributes to the development of dental caries. The aim of the study was to evaluate and compare the efficacy of 3 different fluoride varnishes against Candida albicans in the prevention of dental caries before and immediately after fluoride varnish application and also over a period of 1 week, 1 month and 3 months. METHODOLOGY: A sample size of 60 children’s aged between 6-12 years were randomly selected by block randomization and divided into 3 groups: Group 1 MI Varnish, Group 2 Clinpro XT varnish and Group 3 Flour Protector varnish. Unstimulated saliva samples were collected before and after the application of fluoride varnishes (collected immediately after application, after 1 week, 1 month and 3 months) and were sent for microbiological analysis. The pH of the samples were evaluated by Indikrom paper strips. The results obtained were statistically analysed by mean, standard deviation and One way ANOVA. RESULTS: MI varnish showed a significant drop in Candida albicans followed by Clinpro XT varnish and Fluor Protector Varnish whereas no significant difference were seen in pH. CONCLUSION: The results of the study shows that MI Varnish, Clinpro XT Varnish and Fluor Protector Varnish have antifungal effect on Candida albicans. MI Varnish showed its more profound effect.

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“…Similar studies, where pH of saliva was determined during chewing xylitol gum, used a commercial pH indicator [34] or a benchtop pH meter for measurements of pH [35][36][37][38][39][40]. The measurements of the amount of O 2 and CO 2 in saliva samples are rare in the literature and the proposed solutions are based on the chemical and electrochemical reactions and calculations [41].…”

Section: Discussionmentioning

confidence: 99%

Microfluidic Platform for Examination of Effect of Chewing Xylitol Gum on Salivary pH, O2, and CO2

et al. 2021

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Miniaturization of different measurement processes and a scaled-down approach open the possibility for rapid measurements with the small amounts of samples and reagents into a compact platform with integrated sensors and different measuring components. In this paper, we report a microfluidic approach for measurements of salivary pH, dissolved O2, and CO2 during chewing xylitol gum. The study was done with the samples of 30 healthy volunteers who were chewing a xylitol gum, and the measurements were performed in the microfluidic (MF) chip with integrated commercial PreSens sensors. Xylitol exhibited a significant effect on the pH of saliva in terms of its initial drop, which was the most significant between the 5th and 10th minutes. The effect of xylitol on the amount of oxygen and carbon dioxide in saliva cannot be confirmed. The employed microfluidic platform was shown to be applicable and effective in the analysis of salivary biomarkers relevant to caries development.

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Effect of different chewing gums on dental plaque pH, salivary pH, and buffering capacity in children: A randomized controlled trial

Cited by 5 publications

References 0 publications

A Comparative study of the Clinical and Microbiological Effects of Fluoride, Xylitol and Combined Fluoride-Xylitol Toothpastes in Children

A Comparative study of the Clinical and Microbiological Effects of Fluoride, Xylitol and Combined Fluoride-Xylitol Toothpastes in Children

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

Microfluidic Platform for Examination of Effect of Chewing Xylitol Gum on Salivary pH, O2, and CO2

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