Effect of Different Orifice Diameter on The Flow Characteristic in Pressurized Metered Dose Inhaler by Using CFD

Rahman, Muhammad Faqhrurrazi Abd; Asmuin, Norzelawati; Nasir, Nurul Fitriah; Taib, Ishkrizat; Mat, Mohamad Nur Hidayat; Khairulfuaad, Riyadhthusollehan

doi:10.37934/cfdl.12.3.3949

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…The 3D geometry of AerospaAcer was drawn based on earlier research (copyrighted with the number LY2020002678) using SOLIDWORK 2019. SOLIDWORK software is a computer aided design, CAD software which researcher nowadays used to draw 3D model for their research [5,11,[13][14][15]. The 3D AerospaAcer model as shown in Figure 3 is drawn using some tool features provided in the software.…”

Section: Methodology 21 3d Geometry Model Of Aerospaacermentioning

confidence: 99%

CFD Analysis for Valve-Holding Camber Permanent Inhaler Spacer (AerospaAcer) with Different Valves

Riyadhthusollehan Khairulfuaad,

Norzelawati Asmuin,

Juntakan Taweekun

et al. 2024

CFDL

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During the COVID-19 pandemic, data statistics showed that patients with respiratory problems become infected. One of the therapy techniques for the respiratory condition was the use of a metered-dose inhaler and spacer. The objective of this paper is to determine the flow parameters of three types of valves which is duckbill valve, cross slit valve and umbrella valve in inhaler spacer to compare fluid flow between valve Previous researchers chose the duckbill valve to control fluid flow in inhaler spacer. The flow characteristics are unaffected by the materials used in the new disposable inhaler spacers, such as paper and polylactic acid (PLA). Several design valves reduced the skewness below 0.94 by suppressing the fillet and chamfer. ANSYS Workbench Fluent 19.2 is used to calculate flow parameters such as turbulence kinetic energy (TKE), turbulence eddy dissipation (TED), velocity, particle velocity magnitude, streamline, and vector velocity. The setup input data is based on the previous researcher's specified parameters such as viscosity model, drug characteristics (salbutamol and propellant), discrete phase model (DPM) equal to 80, boundary condition model, and SIMPLE technique. For the three types of valves, the nozzle injection used a 0.50-millimetre dimension. The simulation work is cross-checked against the results of prior simulations. Within each iteration, the transient flow employed a time step size of 0.01 for 200 steps. The results show that computational analysis can distinguish between models of varying complexity. The TED, TKE, and velocity graphs showed the approximate value between the model geometries. Overall, the study was successful in achieving the desired velocity magnitude in terms of visual and graph representations of the various valve.

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Section: Methodology 21 3d Geometry Model Of Aerospaacermentioning

confidence: 99%

CFD Analysis for Valve-Holding Camber Permanent Inhaler Spacer (AerospaAcer) with Different Valves

Riyadhthusollehan Khairulfuaad,

Norzelawati Asmuin,

Juntakan Taweekun

et al. 2024

CFDL

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“…There are four processes to generate the mesh, which start with specifying the global mesh setting, inserting a local mesh setting, generating the mesh, and checking mesh quality. The grid independent test (GIT) was required to select the mesh size [11].…”

Section: Meshing Of Stented Femoral Popliteal Artery Modelmentioning

confidence: 99%

Analysis of Hemodynamic on Different Stent Strut Configurations in Femoral Popliteal Artery

Razhali

Taib

2022

CFDL

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Peripheral arterial disease is a narrowing of the peripheral arteries that might result in blockage if not immediately treated. Normally, an invasive technique called stenting is used at the stenosed arterial region to restore normal blood flow. Furthermore, the impact of physiological stresses on the stented arterial wall may worsen the condition and divert blood away from the main direction of flow. This phenomenon may promote the formation of thrombosis in the stented artery due to the presenting flow recirculation. This study aims to investigate the effect of physiological loads with different hemodynamic factors on the strut configuration in Peripheral arterial. The computational fluid dynamics (CFD) method is governed by continuity and Navier-Stokes equations were implemented. Three-dimensional geometries of the different strut configurations inserted into the peripheral artery are modelled. Each of the struts has different characteristics in terms of strut angle and the number of strut configurations. Due to hemodynamic differences, the pulsatile waveform of the velocity and pressure at the peak systole time were investigated. Hemodynamic factors analysed in this study consist of wall shear stress (WSS), velocity, and pressure. From the result, the prediction of thrombosis formation is around 30% higher for the largest number of strut design. The lowest formation of thrombosis was seen with the fewer strut configurations and the reduction of the strut angle with an overall percentage of 15%.

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Effect of Different Orifice Diameter on The Flow Characteristic in Pressurized Metered Dose Inhaler by Using CFD

Cited by 2 publications

References 17 publications

CFD Analysis for Valve-Holding Camber Permanent Inhaler Spacer (AerospaAcer) with Different Valves

CFD Analysis for Valve-Holding Camber Permanent Inhaler Spacer (AerospaAcer) with Different Valves

Analysis of Hemodynamic on Different Stent Strut Configurations in Femoral Popliteal Artery

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