Effect of Dimethoate and Chlorpyrifos in Hepatic and Renal Function of People Belonging to Risk Groups in Iraklia Serres (N. Greece)

Andreadis, Georgios; Albanis, T. A.; Andreadou, Elisabeth; Mitka, S.; Eleftheriou, F.; Lampropoulou, Dionysia; Avramidis, N.; Patoucheas, D.

doi:10.9734/bjmmr/2014/5828

Cited by 6 publications

(3 citation statements)

References 13 publications

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“…Several studies have reported that CP has adverse effects on sperm activity and hepatic and renal systems. Prenatal exposure is strongly related to low birth weight, small head size, and delayed brain development or neurological disorder in children (Andreadis et al 2014 ).…”

Section: Introductionmentioning

confidence: 99%

Degradation insight of organophosphate pesticide chlorpyrifos through novel intermediate 2,6-dihydroxypyridine by Arthrobacter sp. HM01

Shah

Patel

Trivedi

et al. 2022

Bioresour. Bioprocess.

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Organophosphates (OPs) are hazardous pesticides, but an indispensable part of modern agriculture; collaterally contaminating agricultural soil and surrounding water. They have raised serious food safety and environmental toxicity that adversely affect the terrestrial and aquatic ecosystems and therefore, it become essential to develop a rapid bioremediation technique for restoring the pristine environment. A newly OPs degrading Arthrobacter sp. HM01 was isolated from pesticide-contaminated soil and identified by a ribotyping (16S rRNA) method. Genus Arthrobacter has not been previously reported in chlorpyrifos (CP) degradation, which shows 99% CP (100 mg L−1) degradation within 10 h in mMSM medium and also shows tolerance to a high concentration (1000 mg L−1) of CP. HM01 utilized a broad range of OPs pesticides and other aromatic pollutants including intermediates of CP degradation as sole carbon sources. The maximum CP degradation was obtained at pH 7 and 32 °C. During the degradation, a newly identified intermediate 2,6-dihydroxypyridine was detected through TLC/HPLC/LCMS analysis and a putative pathway was proposed for its degradation. The study also revealed that the organophosphate hydrolase (opdH) gene was responsible for CP degradation, and the opdH-enzyme was located intracellularly. The opdH enzyme was characterized from cell free extract for its optimum pH and temperature requirement, which was 7.0 and 50 °C, respectively. Thus, the results revealed the true potential of HM01 for OPs-bioremediation. Moreover, the strain HM01 showed the fastest rate of CP degradation, among the reported Arthrobacter sp. Graphical Abstract

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Section: Introductionmentioning

confidence: 99%

Degradation insight of organophosphate pesticide chlorpyrifos through novel intermediate 2,6-dihydroxypyridine by Arthrobacter sp. HM01

Shah

Patel

Trivedi

et al. 2022

Bioresour. Bioprocess.

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“…Thus, complete hematology analysis and at least some biochemical analytes such as albumin, aspartate aminotransferase (AST) and total protein (TP) content, should be tested (Gómez et al., 2016). Moreover, these biomarkers must be measured to accomplish an integral evaluation of the species considering possible physiologic alterations caused by a toxic effect of the pesticides or by other environmental pollutants (Andreadis et al., 2014).…”

Section: Introductionmentioning

confidence: 99%

Differences in plasmatic butyrylcholinesterases (BChE) values between Pacific and Caribbean populations of terciopelo (Bothrops asper) in Costa Rica

Arguedas

Gómez

Alcázar

et al. 2019

Heliyon

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The terciopelo (Bothrops asper) inhabits human-modified environments such as agricultural areas, becoming more prone to be exposed to organophosphate insecticides. These chemicals can inhibit plasmatic butyrylcholinesterases (BChE) activity in B. asper. Caribbean and Pacific populations of B. asper belong to two divergent lineages that exhibit robust genetic partitioning; however, differences across versants in biochemistry and hematology have not yet been examined, especially in BChE variations. This study aims to evaluate the differences of BChE plasmatic values, hematology parameters, and some biochemical analytes as biomarkers in the presence of organophosphates between the Pacific and Caribbean population of B. asper in Costa Rica. A total of 89 snakes (41 Pacific and 48 Caribbean) were used, and hematology parameter, albumin, aspartate aminotransferase (AST), total protein and BChEs were evaluated. Differences in hemoglobin content, thrombocytes, white cell count, AST, and BChE values were found between both versants. Intrinsic genetic factors might influence the variation found in BChE and AST values in the snakes sampled from both versants; moreover, understanding this variation in BChE and AST values across the B. asper's distribution can be useful in future ecotoxicology, biomonitoring, genetic and other clinical/health studies.

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“…In recent years, it has also been widely employed worldwide for the control of household and subterranean pests . However, CP has been reported to have side effects on sperm activity and hepatic and renal functions of humans. Prenatal exposure to CP has a strong link with low birth weight, smaller head size of infants, and delayed neurodevelopment of children. , CP has also been identified as an environmental breast cancer risk factor .…”

Section: Introductionmentioning

confidence: 99%

Isolation, Colonization, and Chlorpyrifos Degradation Mediation of the Endophytic Bacterium Sphingomonas Strain HJY in Chinese Chives (Allium tuberosum)

Feng

et al. 2017

J. Agric. Food Chem.

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The endophyte-plant interaction can benefit the host in many different ways. An endophytic bacterium strain (HJY) capable of degrading chlorpyrifos (CP) was isolated from Chinese chives (Allium tuberosum Rottl. ex Spreng). The isolated bacterium HJY classified as Sphingomonas sp. strain HJY could use CP as the sole carbon source. After being marked with the gfp gene, the colonization and distribution of strain HJY-gfp were directly observed in different tissues of Chinese chives with a confocal laser scanning microscope. The inoculation of strain HJY-gfp in Chinese chives resulted in a higher degradation of CP inside the plants than in uninoculated plants. With drench application, up to 70 and 66% of CP were removed from shoots and roots of inoculated Chinese chives, respectively. Moreover, up to 75% of CP was removed from the soil containing plants inoculated with HJY-gfp. With foliage application, the applied concentration of chlorpyrifos affected the degradation performance of strain HJY in Chinese chives. Significant differences were observed only between inoculated and uninoculated Chinese chives with the low applied concentration of CP. Together, other than natural endophyte-assisted plant protection for food safety, the interaction of HJY and plant may be also a promising strategy for in situ bioremediation of soil contaminated with CP.

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Effect of Dimethoate and Chlorpyrifos in Hepatic and Renal Function of People Belonging to Risk Groups in Iraklia Serres (N. Greece)

Cited by 6 publications

References 13 publications

Degradation insight of organophosphate pesticide chlorpyrifos through novel intermediate 2,6-dihydroxypyridine by Arthrobacter sp. HM01

Degradation insight of organophosphate pesticide chlorpyrifos through novel intermediate 2,6-dihydroxypyridine by Arthrobacter sp. HM01

Differences in plasmatic butyrylcholinesterases (BChE) values between Pacific and Caribbean populations of terciopelo (Bothrops asper) in Costa Rica

Isolation, Colonization, and Chlorpyrifos Degradation Mediation of the Endophytic Bacterium Sphingomonas Strain HJY in Chinese Chives (Allium tuberosum)

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