Effect of Early Supraglottic Airway Device Insertion on Chest Compression Fraction during Simulated Out-of-Hospital Cardiac Arrest: Randomized Controlled Trial

Abstract

Early insertion of a supraglottic airway (SGA) device could improve CCF by allowing providers to perform continuous chest compressions or by shortening the interruptions needed to deliver ventilations. SGA devices do not require the same expertise as endotracheal intubation. This study aimed to determine whether the immediate insertion of an i-gel® while providing continuous chest compressions with asynchronous ventilations could generate higher CCFs than the standard 30:2 approach using a face-mask in a simulation of OHCA. A multicenter, parallel, randomised, superiority, simulation study was carried out. The primary outcome was the difference in CCF during the first two minutes of resuscitation. Overall and per-cycle CCF, quality of compressions and ventilations parameters were also compared. Among 13 teams of two participants, the early insertion of an i-gel® resulted in higher CCFs during the first two minutes (89.0% vs 83.6%, p=0.001). Overall and per-cycle CCF were consistently higher in the i-gel® group, even after the 30:2 alternation had been resumed. In this group, ventilation parameters were enhanced, but compressions were significantly shallower (4.6 cm vs 5.2 cm, p=0.007). This latter issue must be addressed before clinical trials can be considered.Trial registration: NCT04736446 (03/02/2021)