Effect of Egg White on Serum Cholesterol Concentration in Young Women.

Abstract

SummaryIn a previous study we observed favorable effects of egg white on serum lipids in rats and mice. The present study was designed to elucidate these effects in 24 female university students with moderate hypercholesterolemia. About 30% of total protein was supplied with egg white, tofu or cheese. The experiment was conducted for a complete menstruation cycle of each subject. Lipid intake was about 30% of total energy intake. The energy intake of each subject was constant throughout the experiment. Body weight was measured every morning. Daily activity was measured by a pedometer. Blood was withdrawn after an overnight fast on the first, 15th and last days and serum lipids were measured. Body weight and daily activity were maintained in all the groups throughout the experiment. The egg white group showed a similar decrease in the total cholesterol (Total-C) concentration but a greater increase of high-density lipoprotein cholesterol (HDL-C) concentration as compared to the tofu group and a greater decrease in Total-C and low-density lipoprotein cholesterol (LDL-C) concentrations and a greater increase in the HDL-C concentration as compared to the cheese group (p<0.05). The results indicate the favorable effects of egg white in the control of hypercholesterolemia.

The Effect of the Consumption of Egg on Serum Lipids and Antioxidant Status in Healthy Subjects

“…When lipoprotein particle size and subclasses were analyzed by nuclear magnetic resonance (NMR), significant increases in both LDL and HDL particles as well as an increase in lecithin cholesterol acyltransferase (LCAT) activity were observed by whole egg consumption (16). It has also previously been reported that egg white protein lower the concentration of serum cholesterol by inhibiting cholesterol absorption in animal experiments and clinical trials (17,18). The lack of the increase of serum cholesterol could be attributed to the relatively low amount of loaded cholesterol and to the alteration of the absorption and reverse transport of cholesterol caused by egg components.…”

A Cattle Heart Protein Hydrolysate Ameliorates Hypercholesterolemia Accompanied by Suppression of the Cholesterol Absorption in Rats and Caco-2 Cells

“…The apparently complex effects and mechanisms involved in the cholesterolemic responses to other dietary animal proteins have yet to be completely elucidated. Recent studies have confirmed that a hypocholesterolemic action can be found in animal proteins such as milk whey protein 5,6) and egg white protein 7,8) comparable to that of milk casein.…”

Consumption of Pork-Liver Protein Hydrolysate Reduces Body Fat in Otsuka Long-Evans Tokushima Fatty Rats by Suppressing Hepatic Lipogenesis

“…On the other hand, some reports have been published on the hypocholesterolemic effect of animal products, such as egg white protein, 14) papain-hydrolyzed pork meat, 15) and peptides derived from bovine milk betalactoglobulin. 16) Animal liver has traditionally been used as a food ingredient to supply several nutrients.…”