2021
DOI: 10.3389/fnut.2021.647782
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Effect of Enzymatic Hydrolysis on the Zinc Binding Capacity and in vitro Gastrointestinal Stability of Peptides Derived From Pumpkin (Cucurbita pepo L.) Seeds

Abstract: Zinc is a crucial micronutrient for maintaining body immune system and metabolism function. However, insufficient intake from diet may lead to zinc deficiency and impair normal body function. In addition, conventional zinc salts supplementation has the disadvantage of low bioavailability since the zinc ions may be easily chelated by dietary fiber or phytate commonly found in diets rich in plants, and form precipitates that cannot be absorbed. Therefore, the objective of the present study is to prepare pumpkin … Show more

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Cited by 29 publications
(12 citation statements)
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“…The PSPH was prepared by papain hydrolysis as described before (Lu et al., 2021). Specifically, the pumpkin seed protein powder was evenly dispersed in deionized water (4%, w/v) and boiled for 15 min to inactivate the endogenous enzymes.…”
Section: Methodsmentioning
confidence: 99%
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“…The PSPH was prepared by papain hydrolysis as described before (Lu et al., 2021). Specifically, the pumpkin seed protein powder was evenly dispersed in deionized water (4%, w/v) and boiled for 15 min to inactivate the endogenous enzymes.…”
Section: Methodsmentioning
confidence: 99%
“…The gastrointestinal stabilities of synthesized peptides zinc chelates were determined and expressed using the methods mentioned in our previous work (Lu et al., 2021). The simulated gastric juice was prepared by dissolving pepsin in 0.1 M hydrochloric acid at pH 2.0.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Zinc is an integral part of more than 200 enzymes in mammals, directly involved in various physiological processes, such as DNA and protein synthesis, proliferation, differentiation, and apoptosis in the entire life ( 1 4 ). Indeed, the deficiency of zinc could cause numerous metabolic disorders, such as oxidative stress or immune system-related diseases, and may even increase COVID-19 infectious risk ( 5 7 ). In recent years, zinc sources have experienced the development process from inorganic zinc to organic zinc form, including amino acid-chelated zinc ( 8 ).…”
Section: Introductionmentioning
confidence: 99%
“…Встановлено, що до складу дієтичних добавок для підтримки функції органів травлення включено сировини 109 лікарських рослин. Найчастіше зустрічаються розторопша плямиста Silybum marianum (Bahmani, 2015) (147 позицій), ромашка лікарська Chamomilla recutita(Rexhepi, 2021) (88 позицій), м'ята перцева Mentha piperita(Mahendran, 2020)…”
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