Effect of erosive and abrasive stress on sealing ability of different desensitizers: In-vitro study

Abstract

This in vitro study examined the sealing ability of different desensitizing agents under a chemo-mechanical stress condition. For the study, a total of 144 extracted, caries-free human third molars were used to produce 1 mm-thick dentin discs. The specimens were divided randomly into four groups: Superseal (SS), Gluma (GL), Gluma Self-etch (GS), and Tooth Coat (TC). For each group, the permeability was measured before and after applying the desensitizer, after being exposed to Coca Cola for 5 minutes, and after 3150 strokes of a brushing abrasion. The decrease in permeability after the erosive and abrasive stress was analyzed by ANOVA and Tukey post hoc test. As a result, the dentin permeability decreased significantly for all desensitizers immediately after application (p < 0.05). SS and GS showed a significant difference in permeability reduction observed immediately after application and after acid action with Coca Cola (p < 0.05). After brushing abrasion, the permeability reduction decreased significantly for all desensitizers tested in this study (p < 0.05). TC showed the largest decrease in dentinal permeability compared to that of the other desensitizers and the differences were significant after brushing abrasion (p < 0.05). All tested desensitizers were effective in reducing dentin permeability. The behavioral characteristics under erosive and abrasive stress varied according to the products used. TC exhibited excellent sealing ability among the other desensitizers.

An One-Year Randomised Controlled Clinical Trial to Assess the Effects of Two Desensitising Agents on Reducing Post-operative Sensitivity After Composite Restorations

“…Through the coagulation of the plasmatic proteins in the dentinal uid, glutaraldehyde functions as a biological xative, leading to the formation of a precipitate primarily composed of plasma proteins, including albumin. The xation process occurs as the amino groups of dentin collagen intertwine with the two aldehyde groups in glutaraldehyde, forming septa that hinder pulp uid ow within the tubule and thus reduce post operative sensitivity [20]. This precipitate contributes to the partial or complete blockage of dentin tubules.…”

Effect of Diode Laser and Iontophoresis with Aqueous Extract of Nigella sativa and Fluoride-Based-Agent on Dentin Permeability

“…A fluorides-based agent was selected for this study since this fluoride compound in particular was found in several previous studies to provide an optimal dentinal tubule occlusion with reduction of dentin permeability (21) . Fluorides decrease the permeability, possibly by precipitation of insoluble calcium fluoride within the tubules (22) .…”

Successful management of dentin hypersensitivity: A narrative review

“…[43][44][45] Although chemical occlusion of dentinal tubules using fluoride, nitrate, and oxalate is common, its effects are not immediate and less efficient in withstanding acid challenges and mechanical stress. 32,46,47…”