Effect of Estrogen and Progesterone on Early Embryonic Mortality in Ovariectomized Gilts

Day, Billy N.; Anderson, Lloyd L.; Emmerson, M. A.; Hazel, L. N.; Melampy, R. M.

doi:10.2527/jas1959.182607x

Cited by 32 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Generation of precursor metabolites and energy (8,6), cellular respiration ( Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (3,12), nuclear-transcribed mRNA catabolic process (3,11), mRNA catabolic process (3, 8.6) 1.17 n.r. of cellular protein metabolic process (6, 4.1), n.r.…”

Section: Gene Expression In Uterine Tissue Of Pregnant Sowsmentioning

confidence: 99%

“…57 Response to bacterium (4, 7.2), response to molecule of bacterial origin (3,12), response to organic substance (6, 2.9) 1. 48 Monocarboxylic acid transport (3,21), carboxylic acid transport (3, 7.1), organic acid transport (3, 7) 1.…”

Section: Analysis Of Gene Expression Patterns Over Implantation Timementioning

confidence: 99%

“…During the firstphase of implantation, embryonic mortality can reach 22%, representing the major period of embryonic mortality [10]. Embryonic mortality is 17% on Day 18 of gestation, and up to 30% on Day 25 of gestation [11,12]. Meishan pigs demonstrate high prolificacy.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Differential Gene Expression in Uterine Endometrium During Implantation in Pigs1

Xiao

Chen

et al. 2015

Biology of Reproduction

View full text Add to dashboard Cite

Embryonic mortality during the implantation period strongly affects litter size in pigs. To analyze the differentially expressed genes (DEGs) in the endometrium during implantation and further to identify candidate genes for litter size, tissues of endometrial attachment sites and intersites were collected from nine pregnant sows on Days 13, 18, and 24 of pregnancy. Endometrium tissue was also collected from another three nonpregnant sows. Samples were hybridized to the porcine Agilent GeneChip microarray. The analysis of gene expression patterns over the implantation period revealed 858 DEGs at endometrial attachment sites. Comparisons of the gene files of attachment sites and intersites revealed 12, 51, and 89 DEGs on Days 13, 18, and 24 of pregnancy, respectively. Annotated function was used to identify overrepresented genetic processes, and several biological processes were considered as the most enriched. Genes related to vascular development, proteolysis, RNA metabolism and translation, protein modification, immune response, and hormone-related are discussed in detail. Then we combined microarray technology and linkage analysis to select powerful candidate genes for quantitative trait loci affecting pig litter size. Eighty-seven DEGs were located in quantitative trait loci related to litter size, that is, total number born and number born alive. Those candidate genes were thought to affect litter size by influencing embryonic implantation. Furthermore, single nucleotide polymorphism of VEGFA was shown to be associated with litter size in pigs. This study identified candidate genes for litter size that were related to embryonic implantation and could be a resource for target studies of genetic markers for litter size in pigs.

show abstract

Section: Gene Expression In Uterine Tissue Of Pregnant Sowsmentioning

confidence: 99%

Section: Analysis Of Gene Expression Patterns Over Implantation Timementioning

confidence: 99%

See 1 more Smart Citation

Differential Gene Expression in Uterine Endometrium During Implantation in Pigs1

Xiao

Chen

et al. 2015

Biology of Reproduction

View full text Add to dashboard Cite

show abstract

“…Although more investigations have been carried out in the pig than in other farm animals, the results are not conclusive. Exogenous progesterone has been found to increase embryonic death (Sammelwitz, Dziuk & Nalbandov, 1956; Spies, Zimmerman, Self & Casida, 1959) or to have no effect on embryonic death (Haines, Warnick & Wallace, 1958) but when combined with an oestrogen to improve embryonic survival Day et al, 1959). An increase in embryonic death in the ewe with the use of progesterone has been reported (Kiracofe & Gossett, 1960).…”

Section: Extent Of Prenatal Mortalitymentioning

confidence: 99%

Prenatal Mortality in Farm Animals

Hanly¹

1961

Reproduction

View full text Add to dashboard Cite

“…It was report ed that a 1:1000 ratio of estrone and progesterone was decided ly inferior to a 1:2000 ratio in reducing early embryonic mortal ity. Using ovariectomized gilts as experimental animals, Day et al (1959) also demonstrated the significance of a proper estrogen-progesterone ratio in the maintenance of pregnancy.…”

Section: Literature Review Embryonic Survivalmentioning

confidence: 99%

Luteal function and embryonic survival in swine

Schultz

View full text Add to dashboard Cite

Effect of Estrogen and Progesterone on Early Embryonic Mortality in Ovariectomized Gilts

Cited by 32 publications

References 0 publications

Differential Gene Expression in Uterine Endometrium During Implantation in Pigs1

Differential Gene Expression in Uterine Endometrium During Implantation in Pigs1

Prenatal Mortality in Farm Animals

Luteal function and embryonic survival in swine

Contact Info

Product

Resources

About