Effect of exercise training on V̇O2peak and left ventricular systolic function in recent cardiac transplant recipients

Haykowsky, Mark J.; Eves, Neil D.; Figgures, Linda; McLean, Allen; Koller, M; Taylor, Dylan; Tymchak, Wayne

doi:10.1016/j.amjcard.2004.12.049

Cited by 28 publications

(23 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Heart transplant recipients (HTR) have severely reduced aerobic capacity (VO 2peak ) (1)(2)(3) that is due, in part, to a blunted exercise cardiovascular reserve (1)(2)(3) associated with cardiac allograft denervation (1,3,4), diastolic dysfunction (1,3,5) and impaired peripheral vascular function (2,6). In addition, HTR also have decreased muscle strength (7) and skeletal muscle mass (8) (6,(9)(10)(11)(12)(13)(14)(15)…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Exercise Training Improves Aerobic Capacity and Skeletal Muscle Function in Heart Transplant Recipients

Haykowsky

Taylor

Kim

et al. 2009

American Journal of Transplantation

View full text Add to dashboard Cite

The aim of this study was to examine the effects of 12 weeks of supervised aerobic and strength training (SET) versus no-training (NT) on peak aerobic power (VO 2peak ), submaximal exercise left ventricular (LV) systolic function, peripheral vascular function, lean tissue mass and maximal strength in clinically stable heart transplant recipients (HTR). Forty-three HTR were randomly assigned to 12 weeks of SET (n = 22; age: 57 ± 10 years; time posttransplant: 5.4 ± 4.9 years) or NT (n = 21; age: 59 ± 11 years; time posttransplant: 4.4 ± 3.3 years). The change in VO 2peak (3.11 mL/kg/min, 95% CI: 1.2-5.0 mL/kg/min), leg and total lean tissue mass (0.78 kg, 95% CI: 0.31-1.3 kg and 1.34 kg, 95% CI: 0.34-2.3 kg, respectively), chest-press (10.4 kg, 95% CI: 5.2-15.5 kg) and leg-press strength (34.7 kg, 95% CI: 3.7-65.6 kg) were significantly higher after SET versus NT. No significant change was found for submaximal exercise LV systolic function or brachial artery endothelialdependent or -independent vasodilation. Supervised exercise training is an effective intervention to improve VO 2peak , lean tissue mass and muscle strength in HTR. This training regimen did not improve exercise LV systolic function or brachial artery endothelial function.

show abstract

Section: Introductionmentioning

confidence: 99%

“…In addition, HTR also have decreased muscle strength (7) and skeletal muscle mass (8) (6,(9)(10)(11)(12)(13)(14)(15)…”

Section: Introductionmentioning

confidence: 99%

Exercise Training Improves Aerobic Capacity and Skeletal Muscle Function in Heart Transplant Recipients

Haykowsky

Taylor

Kim

et al. 2009

American Journal of Transplantation

View full text Add to dashboard Cite

show abstract

“…Nonetheless, several studies have shown that exercise training increases endurance capacity. 570,571 Generally, patients may enter medically supervised outpatient exercise programs as soon as they are discharged from the hospital. The exercise prescription is similar to that for other patients with CVD.…”

mentioning

confidence: 99%

Exercise Standards for Testing and Training

Fletcher¹,

Ades²,

Kligfield³

et al. 2013

Circulation

1,685

760

View full text Add to dashboard Cite

“…Resistance training has recently been recognized as a useful therapeutic tool for the treatment of a number of chronic diseases (12)(13)(14)(15)(16)(17)(18)(19) and has been demonstrated to be safe and efficacious for the elderly (20,21) and obese (22) individuals. Similar to aerobic exercise, resistance training has been reported to enhance insulin sensitivity (23)(24)(25), daily energy expenditure (26,27), and quality of life (20,28).…”

mentioning

confidence: 99%