Effect of extraction solvents and plant parts used on the antihyperlipidemic and antioxidant effects of<i>Garcinia atroviridis</i>: a comparative study

Al-Mansoub, Majed Ahmed; Asmawi, Mohd Zaini; Murugaiyah, Vikneswaran

doi:10.1002/jsfa.6456

Cited by 62 publications

(49 citation statements)

References 34 publications

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“…The reducing power of Gsp was determined using the ferric reducing ability of plasma assay (Almansoub, Asmawi, & Murugaiyah, ). A standard curve was prepared using different concentrations (10–100 mmol/L) of FeSO 4 .…”

Section: Methodsmentioning

confidence: 99%

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Physicochemical property, antioxidant activity, and cytoprotective effect of the germinated soybean proteins

Gao

Wang

et al. 2018

Food Science & Nutrition

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Appropriate germination can improve the nutritional value and bioactivity of soybeans; however, few studies have assessed the effect of germination on soybean proteins. This study examined the physicochemical property, antioxidation, and cytoprotective effect of the germinated soybean proteins (Gsp). Gsp was extracted from soybeans which germinated for 0–3 days using the method of alkali‐solution and acid‐isolation extraction. The results showed that germination could digest soybean proteins into the smaller molecules; enhance the degree of hydrolysis, emulsifiability, and foaming capacity; increase the removal rate of ABTS, DPPH, O2−˙, and ˙OH radical; and decrease the reducing power and lipid peroxidation of Gsp. Additionally, Gsp was able to protect HL‐7702 human hepatocyte cells against benzo(a)pyrene (BaP)‐induced cytotoxicity through mediating the cell cycle arrest, suppressing apoptosis, and increasing reactive oxygen species (ROS) levels. This work demonstrated that germination could enhance the physicochemical property and antioxidant activity of Gsp, which also displayed the remarkable cytoprotective effect. This study provided a fundamental basis for substantiating dietary of Gsp used for resistance to oxidation and hepatic injury.

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Section: Methodsmentioning

confidence: 99%

“…The reducing power of Gsp was determined using the ferric reducing ability of plasma assay (Almansoub, Asmawi, & Murugaiyah, 2014).…”

Section: Reducing Power Assaymentioning

confidence: 99%

Physicochemical property, antioxidant activity, and cytoprotective effect of the germinated soybean proteins

Gao

Wang

et al. 2018

Food Science & Nutrition

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“…other study compares different plant part and extraction process in antihyperlipidemic activity in poloxamer 407-induced hyperlipid rat. It was found that aqueous extract of ripe fruit exhibit antihyperlipidaemic activity where total cholesterol and triglyceride was lowered at 34 hours (20). To sum up, the findings indicated and agreed that fruit extract of G.…”

Section: Antihyperlipidemic/antihyperclolesteromic/antiobesity Activimentioning

confidence: 53%

“…other conclusion also include that leaves are better in antioxidant activity compared to stem part. Although such remarks made by previous author, interesting finding by Al-Mansoub et al (20) stated that stem extract also have better antioxidant activity compared to leaves and fruit when extracted using methanol. Leaves part however, show better antioxidant capacity when extracted using water.…”

Section: Antioxidant Activitymentioning

confidence: 82%

Garcinia atroviridis – A review on phytochemicals and pharmacological properties

Taher¹,

Hamidon²,

Susanti³

et al. 2016

Marmara Pharmaceutical Journal

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“…Belinjau / Melinjau Seeds are prepared as crackers, in cooking dishes (soup) and as coffee substitute Bhat and Yahya, 2014;Voon and Kueh, 1999 Mirfat et al Phytochemistry and biological properties of underutilised fruits -Mansoub et al, 2014;Gerten et al, 2015;Salma et al, 2006 Garcinia dulcis…”

Section: Gnetum Gnemonmentioning

confidence: 99%

Underutilised fruits: a review of phytochemistry and biological properties

Mirfat¹,

Amin²,

Kartinee³

et al. 2018

Journal of Food Bioactives

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Underutilised fruits are not only important sources of food and nutrition, but also secure household income especially for rural and farm communities. However, some of the underutilised fruits have not received much attention as compared to commercial fruits. This could be due to their lack of knowledge of their potential values. Hence, information about their health promoting properties is critical to increase the value of underutilised fruit species to enhance their preservation and sustainable use in strengthening food, nutrition, health and livelihood security. This article aims to provide a comprehensive review on the phytochemical properties and biological activities of underutilised fruit species grown in Malaysia focussing on health promoting aspects. With regard to phytochemistry, only 21 species of underutilised fruits have been identified and quantified. Phytochemical investigations of various parts of the fruits have revealed the presence of over 100 phytochemicals which are phenolics, terpenoids, carotenoids and other miscellaneous compounds. About 51 underutilised fruit species have been explored for interesting biological activities (antioxidant, antimicrobial, anticholinesterase, cytotoxicity, antiatherosclerotic, antihyperlipidemia, antidiabetic, cytoprotective, cardioprotective and antiplatelet activities) supporting their diverse traditional uses. Different parts of the fruits have been analysed mainly in vitro and barely in vivo, with pulp being the most dominant. Of all the underutilised fruits studied, Mangifera species and Canarium odontophyllum have been the major focus for researchers. The gaps obtained from this review create further research opportunities to add to the current knowledge of health promoting properties of underutilised fruits in Malaysia. More studies are needed to confirm the health significance and explain their mechanisms of action in order to fully understand the real potential of this underutilised fruit species.

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Effect of extraction solvents and plant parts used on the antihyperlipidemic and antioxidant effects ofGarcinia atroviridis: a comparative study

Cited by 62 publications

References 34 publications

Physicochemical property, antioxidant activity, and cytoprotective effect of the germinated soybean proteins

Physicochemical property, antioxidant activity, and cytoprotective effect of the germinated soybean proteins

Garcinia atroviridis – A review on phytochemicals and pharmacological properties

Underutilised fruits: a review of phytochemistry and biological properties

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