Effect of ferrous ion and ascorbate-induced lipid peroxidation on liposomal membranes

How is leghemoglobin involved in peribacteroid membrane degradation during nodule senescence?

“…The effect of H,O, and iron ions seen here with symbiosomes is similar to that noted in studies on liposomal membranes where lipid peroxidation caused an increase in non-specific permeability of membranes [21]. Thus peroxidized symbiosomes can be considered as bacteroids surrounded by a deteriorating PBM, allowing more direct contact between the microsymbionts and the external medium: the permeability of symbiosomes gradually came to resemble that of the bacteroid.…”

“…It should be noted, however, that under certain conditions lipid peroxidation can occur without inducing significant membrane leakage in the short term [21]. Furthermore, as radical reactions are sitespecific (when formed, radicals must be very close to their target to cause lipid peroxidation), the access of activated Lb to membrane material may limit the reaction in intact symbiosomes.…”

Effects of active oxygen scavengers on the peroxidation of linoleic acid catalyzed by dehydro-L-ascorbic acid or its degradation products.

“…However, it is also true that AsA accelerates the peroxidation or deterioration of lipids (3)(4)(5). As we reported previously (5), AsA in the reaction mixture containing 10% EtOH accelerated linoleic acid (LA) peroxidation, but AsA in 20% EtOH suppressed the LA peroxidation.…”

Antidiabetic and antioxidant activity ofSwietenia mahagoniin streptozotocin-induced diabetic rats

“…Peroxidized lipid has been considered to play a significant role in the pathogenesis of several diseases, and may be taken as a molecular mechanism of cell injury under pathological conditions (Kuaimoto et al, 1981). Lipid peroxidation is usually measured through its catabolite malondialdehyde (MDA) in terms of TBARS as a marker of oxidative stress (Janero, 1990).…”