Effect of fluticasone propionate aqueous nasal spray versus oral prednisone on the hypothalamic-pituitary-adrenal axis

Vargas, Ramón; Dockhorn, Robert J.; Findlay, Steven R.; Korenblat, Phillip E.; Field, Elizabeth A.; Kral, Kenneth M.

doi:10.1016/s0091-6749(98)70085-5

Cited by 62 publications

(30 citation statements)

References 22 publications

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“…In contrast, dexamethasone treatment to OVA induced mice caused significant reduction of serum cortisol levels. This kind of suppression was reported not only for oral corticosteroids but also for inhaled steroids [31][32][33].…”

Section: Discussionsupporting

confidence: 52%

Glycyrrhizin alleviates experimental allergic asthma in mice

Ram¹,

Mabalirajan²,

Das³

et al. 2006

International Immunopharmacology

131

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Section: Discussionsupporting

confidence: 52%

Glycyrrhizin alleviates experimental allergic asthma in mice

Ram¹,

Mabalirajan²,

Das³

et al. 2006

International Immunopharmacology

131

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“…[393][394][395][396][397] Studies in children have shown no clinically significant effect of intranasal corticosteroids on the HPA axis. [398][399][400][401] However, the effect of intranasal corticosteroids on growth, recognizing the variability in individual patient response, may be a better indicator of systemic effects in children, and can occur without an effect on the HPA axis.…”

Section: Hpa Axismentioning

confidence: 99%

The diagnosis and management of rhinitis: An updated practice parameter

Wallace¹,

Dykewicz²,

Bernstein³

et al. 2008

Journal of Allergy and Clinical Immunology

951

953

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“…Thus, the use of oral GC corresponding to 20-30 mg of prednisolone should be limited to a brief period of time (within 1 week) when treating patients with allergic rhinitis. Caution is needed to avoid adverse effects including adrenal cortical suppression and difficulty in withdrawing GC following prolonged administration (longer than 2 weeks) [82].…”

Section: Practical Guideline For Management Of Allergic Rhinitis In Jmentioning

confidence: 99%

Mechanisms and clinical implications of glucocorticosteroids in the treatment of allergic rhinitis

Okano

2009

Clinical and Experimental Immunology

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SummaryAllergic rhinitis is a common airway disease characterized by hypersensitivity, exudation, hypersecretion, inflammatory cell infiltration and remodelling. Intranasal glucocorticosteroids are the most effective drugs for controlling the inflammation caused by allergic rhinitis. Glucocorticosteroids exert anti-inflammatory effects through at least two pathways: the transactivation pathway and the transrepression pathway. Glucocorticosteroids also exert regulatory functions by inducing regulatory cytokines and forkhead box P3 (FoxP3 + ) regulatory T cells. Evidence suggests that intranasal glucocorticosteroids control not only nasal symptoms but also ocular symptoms. In contrast to sedating H1 receptor antagonists, intranasal glucocorticosteroids can improve impaired performance symptoms, such as daytime sleepiness, associated with allergic rhinitis. Recent studies suggest that intranasal glucocorticosteroids might also be useful for the prophylactic treatment of pollinosis; this possibility is supported by the molecular mechanism of the anti-inflammatory action of glucocorticosteroids. These findings suggest that intranasal glucocorticosteroids might be positioned as first-line drugs for the treatment of both perennial and seasonal allergic rhinitis.

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Effect of fluticasone propionate aqueous nasal spray versus oral prednisone on the hypothalamic-pituitary-adrenal axis

Cited by 62 publications

References 22 publications

Glycyrrhizin alleviates experimental allergic asthma in mice

Glycyrrhizin alleviates experimental allergic asthma in mice

The diagnosis and management of rhinitis: An updated practice parameter

Mechanisms and clinical implications of glucocorticosteroids in the treatment of allergic rhinitis

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