Effect of GelMA Hydrogel Coatings on Corrosion Resistance and Biocompatibility of MAO-Coated Mg Alloys

Abstract

Micro-arc oxidation (MAO) treatment is a simple and effective technique to improve the corrosion resistance for magnesium alloys. However, the presence of micro-pores and cracks on the coatings provides paths for corrosive ions to penetrate into and react with the substrate, limiting the long-term corrosion resistance. In this paper, we designed a composite coating with which GelMA hydrogel coatings with varying thicknesses were prepared on the surface of MAO-coated magnesium alloys via a dip-coating method, aiming to improve the biocorrosion resistance and biocompatibility. The surface morphology, the chemical composition of GelMA hydrogels, and the crystallographic structure of magnesium alloys were characterized by scanning electron microscope (SEM), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD), respectively. The corrosion resistance and biocompatibility of all samples were evaluated through electrochemical and biological experiments. The results demonstrated that the addition of GelMA hydrogel could effectively seal the pores and improve the corrosion resistance and biocompatibility of MAO-coated magnesium alloys, especially for the sample with one layer of GelMA hydrogel, showing high cell proliferation rate, and its current density (Icorr) was two orders of magnitude lower than that of the MAO coating. Besides, the balance mechanism between corrosion and protection was proposed. As a result, the GelMA hydrogel coatings are beneficial to the application of MAO-coated magnesium alloys in bone tissue engineering and other fields.

A TGF-loading hydrogel scaffold capable of promoting chondrogenic differentiation for repairing rabbit nasal septum cartilage defect

“…The Fourier transform infrared spectroscopy results showed that the GelMA-T scaffolds had two typical absorption peaks. The absorption peak at 3,289 cm −1 corresponded to the stretching vibration of the N-H peptide bond, whereas the absorption peak at 1,663 cm −1 was the stretching vibration of the C=O double bond (Figure 1B), which is consistent with previously reported results for GelMA (Weng et al, 2020;Da Silva et al, 2021).…”

A novel bioactive polyurethane with controlled degradation and L-Arg release used as strong adhesive tissue patch for hemostasis and promoting wound healing

“…2 . It exhibited absorbance from 3411 to 3289 cm −1 confirming the presence of peptide bonds (mainly N–H stretching) [ 38 ]. The obvious absorbance peak at 1645 cm −1 could be assigned to C O stretching vibration, and the peak at 1531 cm −1 was assigned to C–N stretching plus N–H bending.…”

Corrosion and Wear Behavior of TiO2/TiN Duplex Coatings on Titanium by Plasma Electrolytic Oxidation and Gas Nitriding

“…When a capacitor is omitted from the circuit, no current can flow because, when the capacitor is charged, the current will not pass, and the circuit will be cut off. The dense oxide layer on the surface of the titanium also has this effect and, such as a capacitor after being fully charge, disrupts the electrical circuit by reducing the corrosion rate [ 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 ]. Based on the EIS diagrams and the obtained data, it can be concluded that the corrosion resistance of the sample with plasma electrolytic oxidation coating is better than that of the uncoated sample.…”