Effect of Gibberellic Acid on the Growth, Alkaloid Production, and VLB Content of Catharanthus Roseus

Effects of various elements (Co, Ni, Zn, W, Mn, Cr, B, Mo, Fe, and V), natural and synthetic auxins, cytokinins, and gibberellin on biosynthesis and accumulation of indole alkaloids was studied at increasing concentrations in the model system of Madagascar periwinkle seedlings ( Catharanthus roseus L.). The main types of concentration dependences for the effect of physiologically active compounds under study were evaluated. A possible mechanism of the influence of Zn and auxin on this process was partly clarified. The compounds were shown to modulate various stages in the biosynthesis of monomeric indole alkaloids (catharanthine and vindoline).

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“…However, gibberellin stimulated plant growth and decreased the alkaloid content under field conditions [35,36]. The exception is gibberellin.…”

Section: Resultsmentioning

confidence: 99%

Role of elements and physiologically active compounds in the regulation of synthesis and accumulation of indole alkaloids in Catharanthus roseus L.

Lovkova

Бузук

Sokolova

et al. 2005

Appl Biochem Microbiol

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“…Total alkaloids in leaves and roots were determined by the method for alkaloid analysis described by Higuchi & Bodin (1961). The total alkaloids were calculated as peruvine, as suggested by Masoud et al (1968). The crop was affected by dieback disease caused by Pythium butleri and about 30% plants died from this disease.…”

Section: Methodsmentioning

confidence: 99%

Effect of nitrogen, phosphorus and farmyard manure on yield and alkaloid concentration in Catharanthus roseus (L.) G. Don

1988

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Periwinkle (Catharanthus roseus (L.) G. Don) is an important medicinal plant grown in different parts of India. Its leaves contain vincristine and vinblastin, alkaloids which are used in the treatment of various leukaemias and limphomas, and its roots contain ajmalcine, another alkaloid, used in the manufacture of antihypertensive drugs. Cultivation of periwinkle has recently gained importance in India. The yield of periwinkle can be increased with the use of mineral fertilizers (Pareek et al. 1981, 1982; Rajasekharan et al. 1982; Reghunath & Sethumadhavan, 1982a, b; Hegde, 1986). The effect of fertilizer application on the alkaloid concentration is not clearly established though there are a few reports which suggest that application of N increases alkaloid concentration in roots (Rajasekharan et al. 1982; Reghunath & Sethumadhavan, 1982a) and leaves (Pareek et al. 1982). Therefore, the present experiment was designed to study the effect of application of nitrogen and phosphatic fertilizers and farmyard manure on the root and leaf yields, and total alkaloid concentrations in roots and leaves in Catharanthus roseus (L.) G. Don.

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“…The change in leaf shape has seen from obovate to lanceolate although no effect was seen on flowering (Masoud et al 1968). At the end of final harvesting process, the presence of total alkaloids in the leaves and roots decreased.…”

Section: Growth Regulatorsmentioning

confidence: 97%

Agricultural, Pharmaceutical, and Therapeutic Interior of Catharanthus roseus (L.) G. Don

Barkat

Abul²,

Rahman

2017

Catharanthus Roseus

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Catharanthus roseus (C. roseus) (L.) G. Don known as Madagascar periwinkle (MP) is a popular ornamental plant found in gardens and homes across the world. C. roseus (L.) G. Don has been widely distributed for long enough and gained popularity as diverse application in medicinal uses for a variety of purposes such as antimicrobial, antioxidant, anthelmintic, antifeedant, antisterility, antidiarrheal, and antidiabetic effect and have been used in the treatment of leukemia, Hodgkin's disease, malignant lymphomas, neuroblastoma, Wilms tumor, Kaposi's sarcoma, and mycosis fungoides to improve cerebral blood flow and treat high blood pressure. The pharmacology of the plant was found to be associated mostly especially with the alkaloids that occupies almost all parts of the plant. C. roseus (L.) G. Don is a legendary medicinal plant mostly because of possessing two invaluable antitumor terpenoid indole alkaloids (TIAs), vincristine and vinblastine. The ethnobotanical significance of C. roseus (L.) G. Don is exemplified by its international usage as a traditional remedy for abundant ailments and not only for cancer. TIAs are present only in micro quantities in the plant and are highly poisonous per se rendering a challenge for researchers to increase yield and reduce toxicity. Good agronomic practices ensure generous propagation of healthy plants that serve as a source of bioactive compounds and multitudinous horticultural applications. In this chapter, an attempt has been made to summarize the agricultural, pharmaceutical,

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Effect of Gibberellic Acid on the Growth, Alkaloid Production, and VLB Content of Catharanthus Roseus

Cited by 20 publications

References 8 publications

Role of elements and physiologically active compounds in the regulation of synthesis and accumulation of indole alkaloids in Catharanthus roseus L.

Role of elements and physiologically active compounds in the regulation of synthesis and accumulation of indole alkaloids in Catharanthus roseus L.

Effect of nitrogen, phosphorus and farmyard manure on yield and alkaloid concentration in Catharanthus roseus (L.) G. Don

Agricultural, Pharmaceutical, and Therapeutic Interior of Catharanthus roseus (L.) G. Don

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