Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease

Bordia, A; Verma, Surendra Kumar; Srivastava, K. C.

doi:10.1016/s0952-3278(97)90587-1

Cited by 302 publications

(202 citation statements)

References 9 publications

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“…Similarly there was a highly significant (p<0.001) reduction in PPBG in both the groups. This is supported by studies conducted by Bordia et al 14 However the reduction in PPBG was greater in Group 2. Besides this, there was a highly significant reduction in HbA1c levels in both the groups (p<0.001).…”

Section: Discussionsupporting

confidence: 80%

To study the efficacy and tolerability of fenugreek seed powder as add-on therapy with metformin in patients of type-2 diabetes mellitus

Kaur¹,

Singh²,

Sharma³

et al. 2016

Int J Basic Clin Pharmacol

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Section: Discussionsupporting

confidence: 80%

To study the efficacy and tolerability of fenugreek seed powder as add-on therapy with metformin in patients of type-2 diabetes mellitus

Kaur¹,

Singh²,

Sharma³

et al. 2016

Int J Basic Clin Pharmacol

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“…The results showed that fenugreek supplement significantly reduced the area under the plasma glucose curve and improved glucose tolerance. In the fourth trial [37], forty patients with coronary artery disease and non-insulin-dependent diabetes mellitus and 30 healthy volunteers were given a diet containing 5 g of fenugreek for 3 months. At the end of the study, twenty patients with mild hyperglycemia exhibited a significant reduction in FBS and postprandial glucose levels.…”

Section: Fenugreekmentioning

confidence: 99%

A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements

Deng¹

2012

FNA

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Hyperglycemia is a pathological condition associated with prediabetes and diabetes. The incidence of prediabetes and diabetes is increasing and imposes great burden on healthcare worldwide. Patients with prediabetes and diabetes have significantly increased risk for cardiovascular diseases and other complications. Currently, management of hyperglycemia includes pharmacological interventions, physical exercise, and change of life style and diet. Food supplements have increasingly become attractive alternatives to prevent or treat hyperglycemia, especially for subjects with mild hyperglycemia. This review summarized current patents and patent applications with relevant literature on five commonly used food supplements with claims of hypoglycemic effects, including emblica officinalis (gooseberry), fenugreek, green tea, momordica charantia (bitter melon) and cinnamon. The data from human clinical studies did not support a recommendation for all five supplements to manage hyperglycemia. Fenugreek and composite supplements containing emblica officinalis showed the most consistency in lowering fasting blood sugar (FBS) or glycated hemoglobin (HbA1c) levels in diabetic patients. The hypoglycemic effects of cinnamon and momordica charantia were demonstrated in most of the trials with some exceptions. However, green tea exhibited limited benefits in reducing FBS or HbA1c levels and should not be recommended for managing hyperglycemia. Certain limitations are noticed in a considerable number of clinical studies including small sample size, poor experimental design and considerable variations in participant population, preparation format, daily dose, and treatment duration. Future studies with more defined participants, standardized preparation and dose, and improved trial design and size are warranted.

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“…In this context, a number of research studies have been conducted to examine the possibilities of using various herbs in isolation or in combination (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17). In the present investigation, nine herbal products traditionally in use as preventive or curative agents for various ailments have been combined to form "DeepaniyaVati" for assessing its suitability as hypolipidemic agent.…”

Section: Methodsmentioning

confidence: 99%

Preliminary study on the effect of a herbal formulation “Deepaniyavati” in hyperlipidemia

Surana¹,

Sankhla²,

Dashora³

2000

Indian J Clin Biochem

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To examine the effect of "DeepaniyaVati", a herbal formulation in the management of hyperlipidemia, a randomized group pre -test post -test study trial was carried out on fifty male (30 to 70 yrs) hypedipidemic volunteers who were asked to follow their normal routine diet and activity pattern throughout the investigation period. The formulation, prepared by mixing nine plant products in equal proportion, when given in a daily dose of 2g, twice a day for a period of one month, brought about an observable improvement in all the lipid parameters by significantly reducing total cholesterol (10%), low density lipoprotein cholesterol (12.76%), very low density lipoprotein cholesterol (27.4%), triglycerides (34.7%) and bringing these values much nearer to the normal levels. In control group, no such effect was noticed. A concomitant significant increase in the HDL -C levels suggests the possible utility of "Deepaniya Vati" in the management of hyperlipidemia and the need for further detailed study.

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Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease

Cited by 302 publications

References 9 publications

To study the efficacy and tolerability of fenugreek seed powder as add-on therapy with metformin in patients of type-2 diabetes mellitus

To study the efficacy and tolerability of fenugreek seed powder as add-on therapy with metformin in patients of type-2 diabetes mellitus

A Review of the Hypoglycemic Effects of Five Commonly Used Herbal Food Supplements

Preliminary study on the effect of a herbal formulation “Deepaniyavati” in hyperlipidemia

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