Effect of gluconic acid on piglet growth performance, intestinal microflora, and intestinal wall morphology1

Biagi, Giacomo; Piva, Andrea; Moschini, Maurizio; Vezzali, Enrico; Roth, F. X.

doi:10.2527/2006.842370x

Cited by 75 publications

(66 citation statements)

References 36 publications

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“…The reason is probably that the function of GOD is to act as an antibacterial agent through the production of gluconic acid and H 2 O 2 . Biagi et al (2006) demonstrated that feeding gluconic acid positively influenced the composition and activity of the intestinal microflora of piglets after weaning. It has been reported that sustained oxidative stress through the maintenance of low concentration of H 2 O 2 by GOD's continued catalytic activity to be effective against pathogenic bacteria (Dobbenie et al, 1995;Wu et al, 1995).…”

Section: Resultsmentioning

confidence: 99%

“…Two products of GOD hydrolysis are H 2 O 2 and gluconic acid, which may act as a bacteriocide (Crueger & Crueger, 1990;Rasiah et al, 2005;Costa et al, 2013) and acidity regulator (Nakao et al, 1997;Klein et al, 2002) to reduce the gastric pH, inhibit harmful bacteria and promote the growth of beneficial bacteria. Biagi et al (2006) reported that feeding gluconic acid can improve the growth performance of piglets after weaning. With large-scale production of GOD by fermentation, it is possible to achieve commercial application of GOD in the feed industry (Gao et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

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Effects of glucose oxidase on the growth performance, serum parameters and faecal microflora of piglets

Tang¹,

Yao²,

Gao³

et al. 2016

SA J. An. Sci.

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The experiment was conducted to investigate the effects of diets supplemented with glucose oxidase (GOD) on growth performance, serum parameters and faecal microflora of piglets. One hundred and twelve piglets (35 days old) were randomly assigned to two groups (four replicates per group, half male and half female, and 14 piglets per replicate) and fed a diet with or without 100 U GOD per kg, for 35 days. Feeding GOD caused a higher average daily weight gain and feed intake, and lower feed conversion ratio (FCR) of piglets. No significant difference was observed in the reference values of serum biochemical parameters between the groups fed with or without GOD. The contents of triiodothyronine, thyroxine and growth hormone of piglets fed GOD were higher than those of the control. Moreover, GOD supplementation suppressed the concentration of faecal Salmonella. The results showed that supplementation of GOD to diets promoted growth performance, increased the contents of growth and development-related hormones, and improved the faecal microflora of growing piglets.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Effects of glucose oxidase on the growth performance, serum parameters and faecal microflora of piglets

Tang¹,

Yao²,

Gao³

et al. 2016

SA J. An. Sci.

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“…Da mesma forma, Biagi et al (2006) não notaram efeito dos níveis (0, 3, 6 e 12 ppm) de gluconato de sódio sobre a profundidade de cripta e altura de vilosidade do jejuno, íleo e ceco de suínos aos 70 dias de idade.…”

Section: Methodsunclassified

Desempenho E Características Morfo- Intestinais De Leitoas Desmamadas Alimentadas Com Dietas Contendo Associações De Mananoligossacarídeo

Assis¹,

Luna²,

Caramori³

et al. 2014

AVS

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RESUMO:Avaliou-se o efeito da suplementação de mananoligossacarídeo isolado e associados com ß-glucano e antibiótico em dietas de leitoas durante a fase de creche (21 aos 54 dias de idade) sobre o desempenho, características morfo-histológicas da mucosa intestinal e ocorrência de diarréia. Foram utilizadas 368 leitoas de mesma linhagem, com peso médio de 6,5 kg/unidade experimental, distribuídas em delineamento inteiramente casualizado com quatro tratamentos: 1 -Dieta controle Dieta basal -sem suplementação, 2 -Dieta basal + 1500 g de mananoligossacarídeo ton/ração, 3 -Dieta basal + 500 g de ß-glucano ton/ração e 4 -Dieta basal + 250g Colistina ton/ração, com quatro repetições cada e 23 animais por unidade experimental. O desempenho foi avaliado pelo peso corporal, ganho de peso, consumo de ração e conversão alimentar. As características morfo-histológicas da mucosa intestinal estudadas foram altura de vilosidade, profundidade das criptas intestinais, perímetro de vilosidade e relação altura de vilosidade:profundidade de cripta do duodeno, jejuno e íleo. A ocorrência de diarréia foi observada diariamente pela avaliação da consistência das fezes. Os animais com a dieta contendo a suplementação de mananoligossacarídeo apresentaram melhora de 6,68% no ganho de peso comparada aos demais tratamentos. A utilização de MOS não apresentou diferença (<0,05) na conversão alimentar. Os tratamentos não influenciaram o consumo de ração, incidência de diarreia e as características da morfo-histológicas intestinais. A suplementação de mananoligossacarídeo proporcionou os melhores resultados de ganho de peso e peso final em leitoas de linhagem comercial no período de 21 a 54 dias de idade. Palavras-chave: aditivo; desmame; diarréia; microingredientes nutricionais; morfometria intestinal PERFORMANCE AND MORPHO-INTESTINAL CHARACTERISTICS OF WEANED GILTS FED DIETS CONTAINING COMBINATIONS WITH MANNAN OLIGOSACCHARIDES ABSTRACT:In this study, we evaluated the effect of supplementing mannan oligosaccharides (MOS) solely or combined with ß-glucan and an antibiotics in diets for gilts in the nursery phase (21 to 54 days of age) on the performance, morphohistological characteristics of the intestinal mucosa and occurrence of diarrhea. Three-hundred and sixty-eight gilts from the same strain, with average weight of 6.5 kg/experimental unit, were distributed in a completely randomized design with four treatments: 1 -Control diet (basal diet): no supplementation; 2 -Basal diet + 1,500 g MOS/t of diet; 3 -basal diet + 500 ß-glucan/t of diet; and 4 -Basal diet + 250 g colistin/t of diet, with four replicates each and 23 animals per experimental unit. The performance was evaluated through the body weight, weight gain, feed intake and feed conversion. The morphohistological characteristics of the intestinal mucosa analyzed were villus height, intestinal crypt depth, villus perimeter and villus height:crypt depth ratio of the duodenum, jejunum and ileum. The occurrence of diarrhea was observed daily by evaluating the consistency of feces. The ani...

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“…In addition, Ahmed et al (2014) stated that blends of organic acid supplementation reduce E. coli count and increase Lactobacilli population in weaned pigs. Biagi et al (2006) described a favourable effect of gluconic acid on intestinal microflora, morphology of intestinal villi, and general condition of piglets. Several studies documenting an improvement in growth efficiency have been reported in the literature (Missotten et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Analysis of the effect of dietary protected organic acid blend on lactating sows and their piglets

2016

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-The objective of the present study was to evaluate the effects of blends of dietary protected organic acid supplementation on growth performance, nutrient digestibility, blood profiles, faecal microflora, and gas emission on sows and piglets with emphasis on their modes of action to improve pig performance. A total of 12 sows with an average initial body weight (BW) of 252.40±11.7 kg were used in this trial. Growth performance, blood profiles, and nutrient digestibility of sows and piglets fed protected organic acid were evaluated. The dietary treatments included a basal diet (CON); CON + 0.1% protected organic acid; and CON + 0.2% protected organic acid. The BW and back fat of sows was checked four days prior to farrowing and at the weaning day to calculate BW loss and back fat loss during that period. Inclusion of 0.2% protected organic acid provided a greater digestibility than CON diets throughout the experimental period in lactating sows. Dietary supplementation with 0.2% protected organic acid led to a higher white blood cell and lymphocyte concentration than CON treatment in sucking piglets. Immunoglobulin G concentration observed was greater in protected organic acid groups in lactating sow and sucking piglets. Increased faecal Lactobacillus counts with decreased E. coli concentrations were observed with the diets of protected organic acid fed to lactating sows. The E. coli counts were decreased in weaning piglets. The faecal H 2 S contents were decreased in 0.2% protected organic acid diets during farrowing on day 1. Dietary supplementation with protected organic acid blends beneficially affects the nutrient digestibility, ileal noxious gas (NH 3 and H 2 S) emission, as well as intestinal microbial balance in lactating sows.

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Effect of gluconic acid on piglet growth performance, intestinal microflora, and intestinal wall morphology1

Cited by 75 publications

References 36 publications

Effects of glucose oxidase on the growth performance, serum parameters and faecal microflora of piglets

Effects of glucose oxidase on the growth performance, serum parameters and faecal microflora of piglets

Desempenho E Características Morfo- Intestinais De Leitoas Desmamadas Alimentadas Com Dietas Contendo Associações De Mananoligossacarídeo

Analysis of the effect of dietary protected organic acid blend on lactating sows and their piglets

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