Effect of Green Tea Consumption on Selected Metabolic Biomarkers in Asian Indian Women with Metabolic Syndrome

Abstract

Evidence for benefits of anti-oxidative power of polyphenols in cardiovascular diseases has been established. In the present study, effect of polyphenol rich green tea on selected metabolic biomarkers among Asian Indian women with metabolic syndrome in normal free living condition has been recorded. Thirty three Asian Indian women (>30 y) confirmed as having metabolic syndrome, were enrolled for the present study based on written informed consent. Subjects were asked to consume three cups of green tea daily for a period of four months. Regular telephonic contact and periodic visit to supply the tea were made to ensure compliance with the intervention and maintenance of lifestyle and dietary pattern, as followed before the experimental period. Parameters analyzed at baseline have been used as control data to eliminate individual variation. Doubleblind analysis of selected metabolic markers was done at baseline, 2 months and 4 months of the intervention period. At four months, a significant reduction from baseline was observed in weight (2%), waist circumference (4.5%), blood sugar (4%), glycosylated hemoglobin (4%), total cholesterol (11%) and LDL cholesterol (13%) (p < 0.01). The effect of green tea consumption on BMI, fasting insulin, HDL cholesterol, triglyceride, VLDL, C-reactive protein and homocysteine levels was either inconsistent or non significant. The present study showed that green tea consumption by free living subjects with metabolic syndrome resulted in significant improvements in some of the cardiovascular risk factors including visceral fat, blood sugar and cholesterol level.

Effect of green tea consumption on the metabolic syndrome indices in women: a clinical trial study

“…p2 obtained by independent t-test for comparing the differences between green tea and control groups and <0.05 is considered significant. MET = metabolic equivalent of task; MUFA = mono unsaturated fatty acid; PUFA = polyunsaturated fatty acid; SFA = saturated fatty acid Effect of green tea consumption have also reported a significant reduction in plasma TC, which could be due to longer intervention or higher doses of green tea consumed in these studies, as compared to ours (Ray and Singhania, 2014;Chen et al, 2016).…”

“…In a study by Wang et al (2010) on the effects of GTCs on body composition, it was observed that three-month consumption of green tea extract caused a significant decrease in abdominal fat, waist circumference (WC) and body weight in overweight individuals. "A four-month consumption of green tea in a study of" Ray and Singhania (2014) "and a three-month consumption of green tea extract containing epigallocatechin gallate (EGCG) in a study of " Chen et al (2016) caused a significant reduction in weight, WC, plasma LDL levels and total cholesterol (TC) in women with abdominal obesity.…”

Effects of green tea on glycemic status in female metabolic syndrome patients

“…Among the MeS patients in this study, FSG and HbA1c levels were similar at baseline of the study which is similar to other studies. 17,19 After consumption of green tea, the mean FSG and HbA1c significantly decreased from their baseline as well as it was found lower to the control group after 12 weeks. These findings were supported by others.…”

“…These findings were supported by others. 13,19 On the contrary, one study found significant reduction in HbA1c level with a non-significant change in FSG level and the duration of intervention was short (8 weeks). 12 Another study found no significant difference in FSG and HbA1c level.…”