Effect of Helium-Neon Laser Irradiation on Peripheral Sensory Nerve Latency

Snyder‐Mackler, Lynn; Bork, Christopher E.

doi:10.1093/ptj/68.2.223

Cited by 112 publications

(64 citation statements)

References 8 publications

(12 reference statements)

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“…Another mechanism of the pain weakening can be reduction of the conduction velocity in sensory nerves [29][30][31][32][33]. There are evidences that laser irradiation applied to undamaged skin may produce a direct, local effect on conduction in underlying nerves.…”

Section: Discussionmentioning

confidence: 99%

Analgesic Effects of the Polarized Red+Infrared LED Light

Gulyar¹,

Tamarova²

2017

UCMS

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INTRODUCTION: Our previous studies have shown that exposure of acupuncture points (AP) or painful area of mice to halogen polarized light (PL) effectively weakens the pain. The aim of the study was to determine whether exposure of AP or painful area to LED red-infrared PL evokes analgesic effect. METHODS: The duration of licking the formalin-injected foot (tonic pain) was recorded in control group and mice exposed (5 min, 10 min) to red+infrared LED light on AP E-36 or on the painful area. Power density of the light varied from 0.3 to 16.5 mW/cm 2 . RESULTS: Exposure of AP E-36 or painful area to red-infrared LED PL evoked statistically significant decrease of licking time. The effect depended on the light application duration and its power density. 10-minute light exposition was more effective than 5-minute. The exposure of pain source to LED PL shortened the licking time to 44.1% (at 16.5 mW/cm 2 ) and to 64.4% (at 0.3 mW/cm 2 ). CONCLUSION: The results show the efficacy of pain suppression by exposure of antinociceptive AP or painful area to LED red+infrared PL. The effect depends on the duration of light exposure and its power density.

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Section: Discussionmentioning

confidence: 99%

Analgesic Effects of the Polarized Red+Infrared LED Light

Gulyar¹,

Tamarova²

2017

UCMS

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“…This may be an increase in the synthesis and release of endorphins, as well as a decrease in the release of bradykinin and serotonin in the area of inflammation [44,45]. Another mechanism of easing pain is associated with a decrease in the rate of pain signals in sensory nerves [6,[47][48][49][50][51]. In addition, it has been shown that laser light (especially red) increases blood flow, which is accompanied by an improvement in oxygenation and metabolism, with simultaneous enhancement of lymphatic drainage and weakening of edema in the affected tissue, which also contributes to the relief of pain [7][8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Untitled

2016

UCMS

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Application of the linear polarized polychromatic and monochromatic low-intensity light on the locus of pain or acupuncture point effectively reduces pain. The purpose of this article is to describe what changes in the analgesic effectiveness of polarized light modified by fullerene or graphene filter will occur. The essence of such a change consists in optimizing the distribution of quanta in the light flux (hyperpolarization). In the model of inflammatory somatic pain (formalin test on mice), we investigated the influence of the BIOPTRON device light, which passed through a fullerene or graphene filter, on the intensity of the pain reaction (licking of the affected limb) and on the painless behavior (sleeping, washing, eating, running) of the examined animals. It was established that a 10-minute application to the inflammation locus or to E-36 acupuncture point of fullerene light caused a significant reduction of pain. Analgesia was 43.5% and 38.5%, respectively. All non-painful behavioral reactions (sleeping, washing, running, eating) increased their duration. Duration of sleep compared with the control increased twice (application of light to the locus of inflammation) and 3 times (application to acupuncture point E-36). Light modified by a layer of graphene, when applied to the point of acupuncture E-36, weakened the pain more than if applied to the inflammation locus. Analgesia was 58.9% and 49.5%, respectively. Among the non-painful behavioral reactions, the most significant changes have undergone sleeping and eating behavior. Duration of sleep compared with the control increased 4 times (locus of inflammation) or 2.35 times (acupuncture point E-36). Comparison of these data with the results obtained for monochromatic polarized light ranges showed that they could be attributed to the most effective group of analgesic light factors. Both fullerene and graphene light, along with analgesic, have a powerful sedative effect, surpassing effects in comparison with all other ranges of polarized light. Polarized polychromatic light of the BIOPTRON device, which has passed through a nanophotonic fullerene or graphene filter, acting onto the pain or acupuncture point E-36, significantly reduces pain and has a sedative effect.

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“…Laser application on the distal sensory branch of the radial nerve led to increased latency and decrease velocity. 15 Application on the median nerve in 51 normal volunteers, led to a slight increased latency in sensory antidromic conducting study. 16 Such data were not confirmed by others, whose normal volunteers showed no changes in conduction studies after application of Laser.…”

Section: Introductionmentioning

confidence: 99%