Effect of hemoglobin hydration on the physical properties of erythrocyte cytoplasm and whole blood

The article presents the results of own research on the study of the incidence of osteoporosis and osteopenia in men with different levels of uric acid and the influence of hyperuricemia on the mineral density of bone tissue. The aim of the study was to examine the structural and functional state of bone tissue (indicators of mineral density) in men with different levels of uric acid and to establish the incidence of osteoporosis and osteopenia in patients with hyperuricemia. Materials and methods of research. 140 men aged 50–80 years were examined. Determination of the level of uric acid in the serum was performed using the uricase-peroxidase method. Determination of bone mineral density was performed by DXA on the device «Prodigy». Results. It has been established that the incidence of osteoporosis and osteopenia in men with hyperuricemia is lower compared to men with normouricemia. When dividing by age groups 50–59 years, 60–69 years, 70–79 years in men with hyperuricemia, osteoporosis was detected only in the age group 70–79 years and its incidence was 14% at the level of the lumbar spine (L1–L4) and 14% at the level of the femoral neck (Neack Mean). According to the quarterly distribution according to the level of uric acid, men with the highest level of uric acid had the highest indicators of bone mineral density. Conclusions. Patients with a high level of uric acid have high levels of bone mineral density, so they are less likely to develop diseases such as osteoporosis and osteopenia, which indicates the protective role of uric acid for bone tissue and may be of practical importance when deciding on the issue of drug correction of hyperuricemia.

show abstract

Osmotic resistance of the erythrocyte as an indicator of the functional activity of the cell membrane

MAZUR,

DENYSENKO

2023

Eksp.Klin.fiziol.biohim

View full text Add to dashboard Cite

The presented review describes the structure and features of the functioning of the erythrocyte membrane. Its osmotic resistance is characterized as an indicator of the functional activity of the cell membrane. Changes under the influence of various physical and chemical factors are described. The reasons for its decrease are identified and the direction of maintaining metabolic stability under the influence of various pathological factors is indicated.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Effect of hemoglobin hydration on the physical properties of erythrocyte cytoplasm and whole blood

Cited by 3 publications

References 89 publications

Efficacy of goldenberry in improving obesity-induced hemoglobin conformational structure changes in wistar rats: A biophysical perspective

Efficacy of goldenberry in improving obesity-induced hemoglobin conformational structure changes in wistar rats: A biophysical perspective

Systemic osteoporosis and osteopenia in men with hyperuricemia

Osmotic resistance of the erythrocyte as an indicator of the functional activity of the cell membrane

Contact Info

Product

Resources

About