In this research, an experimental and numerical investigation was conducted to study the flexural behavior of modified slurry-infiltrated fiber concrete slurry-infiltrated fibrous concrete (SIFCON) one-way plates after being subjected to a high temperature. The first part is an experimental work to ensure that the model developed is adequate, while the second part is a 3D finite element modeling of the SIFCON plates with the program ABAQUS using a sequentially coupled thermal displacement analysis. The experimental program included testing eight modified SIFCON plates containing waste powder rubber as a partial substitute for natural sand (0%, 5%, 10%, and 15%). All adopted specimens had identical dimensions (1,000 mm length, 300 mm width, and 50 mm thickness). Four specimens were exposed to fire for 2 hr at a constant temperature of 600°C, after which they were rapidly cooled by spraying them with water. Test results showed that increasing the powder rubber content of burned and unburned modified SIFCON specimens decreased the failure load and increased the specimens’ ductility factor, as well as the ultimate and service deflections. During the test, the failure of SIFCON was observed to be gradual, and the plates remained in contact even after the ultimate load was attained, whereas the failure of the reference mix (without wasted rubber) was observed to be more rapid than that of other SIFCON mixtures. For the flexural test, it gives desirable strength and good fire resistance. This study provides guidance for the study of SIFCON with waste rubber. Overall, the percentage of error between the experimental and numerical results for the load capacity and midspan displacement was about 5.05% and 8.65%, respectively.