2012
DOI: 10.5530/pc.2012.2.5
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Effect of Hordeum vulgare Linn. Seeds on glycolic acid induced urolithiasis in rats

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Cited by 5 publications
(3 citation statements)
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“…Previous studies have indicated that the production of urinary stones is influenced by inorganic phosphate excretion in addition to calcium and oxalate. [20] The excretion of phosphate, calcium and oxalate that was seen in the disease control group of rats in this study is probably the result of calcium phosphate crystal formation. MeCF reduces oxalate, calcium and phosphate excretion, which prevents calculi development.…”
Section: Discussionmentioning
confidence: 50%
See 1 more Smart Citation
“…Previous studies have indicated that the production of urinary stones is influenced by inorganic phosphate excretion in addition to calcium and oxalate. [20] The excretion of phosphate, calcium and oxalate that was seen in the disease control group of rats in this study is probably the result of calcium phosphate crystal formation. MeCF reduces oxalate, calcium and phosphate excretion, which prevents calculi development.…”
Section: Discussionmentioning
confidence: 50%
“…[27] The liver's glycolate oxidase enzyme readily converts glycolic acid to oxalate, which is why the second model uses 3% glycolic acid to induce hyperoxaluria. [20] It was observed that the experimental rats' body weight dropped and they drank less water as a result of the urolithiasis induction. However, after receiving both the standard and test medication, these values returned to their usual levels.…”
Section: Discussionmentioning
confidence: 99%
“…And, there were significant elevated urine output, kidney weight loss and some renal injury markers in glycolic acid induced rats. In vivo antioxidant parameters including lipid peroxidation (MDA), superoxide dismutase (SOD) and catalase (CAT) were also determined [33].…”
Section: Hordeum Vulgarementioning
confidence: 99%