Effect of hyaluronic acid on radiodermatitis in patients with breast cancer: a meta-analysis of randomized controlled trials

Lee, Chieh-Jui; Fang, Hui-Fen; Wang, Chin-Yun; Chou, Kuei‐Ru; Huang, Tsai-Wei

doi:10.1007/s00520-022-06828-7

Cited by 12 publications

(5 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In particular, for locally advanced breast cancer, NAC has become the standard treatment. NAC can not only reduce tumor volume by preoperative chemotherapy but also eradicate metastatic lymph nodes and reduce the grade of cancer, thereby increasing the breast preservation probability, reducing the axillary lymph node dissection rate, avoiding some patients undergoing radical mastectomy, and improving the survival rate and quality of life of patients [ 2 ]. There are many ways to evaluate the effectiveness of breast cancer after NAC.…”

Section: Introductionmentioning

confidence: 99%

Clinical Observation of MRI Scanning Combined with Clinical Nursing for Surgical Breast Cancer Patients

Zhang

Yin

Tao

et al. 2022

International Journal of Analytical Chemistry

View full text Add to dashboard Cite

The aim of this study was to explore the application effect of perioperative nursing care for patients with breast cancer. In this paper, 100 breast cancer patients with lymphatic spread treated by breast surgery in September 2019 to December were selected as the evaluation objects. They were divided into two groups according to preoperative imaging examination, 50 cases in each group. Group A was examined by B-ultrasound before axillary lymphadenectomy, group B was examined by MRI before axillary lymphadenectomy, and group C was examined by B-ultrasound and MRI before axillary lymphadenectomy. The facts in the three groups of disease findings were compared. Compared with the control group, the proportion of negative emotions (such as stress and depression) in the control group decreased (P<0.05). The decrease in blood cortisol was higher than in the control group ( P < 0.05 ). Improving the existing cancer surgery can improve the patient’s heart rate and reduce blood cortisol so as to improve the patient’s joint function and quality of life. The difficulty of nursing patients will also be reduced, which is medically necessary.

show abstract

Section: Introductionmentioning

confidence: 99%

Clinical Observation of MRI Scanning Combined with Clinical Nursing for Surgical Breast Cancer Patients

Zhang

Yin

Tao

et al. 2022

International Journal of Analytical Chemistry

View full text Add to dashboard Cite

show abstract

“…Given these complexities, more evidence is needed to conclusively determine whether Trolamine can be an effective intervention for preventing RD. ols and vitamin E. Moreover, the study demonstrated that hyaluronic acid was more effective in preventing RD in breast cancer patients and had a lower incidence of desquamation events compared to other topical medications [46]. A double-blind, randomized clinical study also indicated that the use of hyaluronic acid cream significantly reduced the incidence of highgrade RD in patients undergoing radiotherapy for head and neck cancer, breast cancer, or pelvic cancer [47].…”

Section: Discussionmentioning

confidence: 90%

The effect of various interventions on the prevention of radiation dermatitis: a network meta-analysis

Cao

2024

Am J Transl Res

View full text Add to dashboard Cite

Objective: High doses of radiation, while effective at destroying tumor tissues, also result in radiation dermatitis (RD) at irradiated sites, which is one of the most common complications in cancer radiotherapy. Currently, no standardized protocols for the prevention and treatment of RD have been established in clinical practices, and severe RD can compromise treatment efficacy and reduce patients' quality of life. This systematic review and network meta-analysis (NMA) aims to compare the effectiveness of various interventions in preventing RD in patients. Methods: As of June 2023, four databases, including PubMed, Embase, Web of Science, and the Cochrane Library, were searched, with a total of 19 interventions obtained for comparative analysis of their effectiveness in preventing RD. The Cochrane risk-of-bias tool was employed to screen literature, extract data, and appraise the quality of the studies by two researchers. Bayesian network meta-analysis (NMA) was conducted utilizing StataSE 15 and R 4.2.3. Results: A total of 33 studies involving 4307 patients were included in this analysis. From the 33 studies, 19 interventions, encompassing Barrier Films and Dressings (BFD)

show abstract

“…Hyaluronic acid (HA) has been used in oncology to reduce radiation dermatitis due to its accepted safety profile and effectiveness in decreasing inflammation. In a recent systematic review by Lee et al (21), HA showed a better effect than other topical drugs and a lower incidence of desquamation events in breast cancer patients. In support of that, Cosention et al discovered that the topical application of HA in patients with inflammatory diseases at the level of the vaginal and anal mucosa, following RT, resulted in an inventive method to help patients control the side effects (22).…”

Section: Hyaluronic Acidmentioning

confidence: 95%

Prophylaxis and Management of Radiation-Induced Dermatitis

Alzanbagi¹,

Alshaqaqiq²,

Alsadi³

et al. 2022

JOHS

View full text Add to dashboard Cite

Radiation dermatitis is an acute skin reaction that occurs as a result of radiotherapy used to treat a range of different cancers. The severity of symptoms ranges from erythema to dry desquamation (dry, flaky skin with itching) to moist desquamation (serious exudate, edema, and blistering). While a variety of topical agents and dressings are used to ameliorate side effects, there is minimal evidence to support their use. This study aimed to review the evidence on radiation-induced dermatitis, its prophylaxis, and its management. Only a few studies have found that specific topical agents have a significant benefit. Film dressings are the most efficient means of preventing acute radiation dermatitis, whereas foam dressings were found to be beneficial in treating it. In a preventive situation, barrier films and silicone-based gel treatments may lower the severity of skin reactions and symptoms and entirely halt the onset of moist desquamation. Radiation dermatitis has been prevented and treated with a variety of topical and systemic medications, but there is not enough data to recommen

show abstract

Effect of hyaluronic acid on radiodermatitis in patients with breast cancer: a meta-analysis of randomized controlled trials

Cited by 12 publications

References 34 publications

Clinical Observation of MRI Scanning Combined with Clinical Nursing for Surgical Breast Cancer Patients

Clinical Observation of MRI Scanning Combined with Clinical Nursing for Surgical Breast Cancer Patients

The effect of various interventions on the prevention of radiation dermatitis: a network meta-analysis

Prophylaxis and Management of Radiation-Induced Dermatitis

Contact Info

Product

Resources

About