Effect of hydrocolloid dressing combined with low molecular weight heparin and calcium on scar hyperplasia in burn patients with venous thromboembolism

Abstract

The purpose of this study is to investigate the effect of hydrocolloid dressing combined with low molecular weight heparin calcium on scar hyperplasia in burn patients with venous thromboembolism. A retrospective analysis was made on 98 patients with burns complicated with venous thromboembolism in Renmin Hospital, Hubei University of Medicine from January 2020 to April 2021. According to different treatment methods, they were divided into a control group (48 cases) and a research group (50 cases), who were given low molecular weight heparin calcium combined with routine treatment and hydrocolloid dressing on the basis of the control group. The wound healing time, dressing change times and infection symptom regression time in the study group were significantly lower than those in the control group (P < .05). After the intervention, the degree of wound pain in both groups was reduced, and the degree of wound pain in the study group was significantly lower than that in the control group, with statistical significance (P < .05). Fibrinogen, activated partial thromboplastin (APPT), D‐dimer, fibrinolytic degradation products, prothrombin time and activated partial prothrombin time of the two groups were all improved. The degree of scar hyperplasia in both groups was improved, and the degree of scar hyperplasia in the study group was significantly better than that in the control group, and the difference was statistically significant (P>.05). Complications in the study group were lower than those in the control group, and the difference was statistically significant (P < .05). The hydrocolloid dressing combined with low molecular weight heparin calcium can effectively shorten the wound healing time and infection symptom regression time of burn patients with venous thromboembolism, reduce the number of dressing changes, reduce the degree of pain, have no influence on coagulation function, reduce the degree of scar, and reduce the incidence of complications.

An Overview of Recent Developments in the Management of Burn Injuries

“…Hydrocolloids are substances that have the ability to form gels or thick, viscous dispersions when in contact with water [130]. They have the ability to absorb small to moderate amounts of exudate, retain moisture in the wound, create a mildly acidic, low-oxygen environment, facilitate capillary growth and accelerate the wound healing process [131]. Some studies suggest the superiority of hydrocolloid dressings over paraffinbased gauze in the treatment of mixed dermal burns in pediatric patients.…”

Nanomotor-hydrogel Delivery System with Enhanced Antibacterial Performance for Wound Treatment

“…Developing new wound dressings with efficient antibacterial action is crucial for treating complex bacterial infections . With the advancement of biomedical technology, the types of wound dressings continue to increase, including hydrogels, hydrocolloids, fibrous dressings, foam dressings, film dressings, etc. − It is of research significance to improve the mechanical and antimicrobial properties of wound dressings and endow them with self-healing properties to achieve the best healing results.…”