Effect of hydrolysable tannins on intestinal morphology, proliferation and apoptosis in entire male pigs

Bilić-Šobot, Diana; Kubale, Valentina; Škrlep, Martin; Čandek-Potokar, Marjeta; Povše, Maja Prevolnik; Fazarinc, Gregor; Škorjanc, Dejan

doi:10.1080/1745039x.2016.1206735

Cited by 54 publications

(54 citation statements)

References 40 publications

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“…Recent in vitro studies have revealed that HTs inhibit the pancreatic α-amylase activity and amylase absorption [26]. The current findings on feed efficiency are in agreement with those of previous studies [5,6] although they contradict the findings ofČandek-Potokar et al [4]. The latter found a significant reduction in feed intake and a concomitant decrease in growth and thus similar feed efficiency with increasing HT levels.…”

Section: Dietary Effects On Growth Performancesupporting

confidence: 88%

“…The results of recent studies have suggested that bioactive compounds, such as hydrolysable tannins (HTs), included in the diets of finisher pigs also have the potential to reduce bacteria-mediated S and I production in the colon, resulting in lower tissue levels of the two boar taint compounds in the adipose tissue [4,5]. In line with these findings, Bilić-Šobot et al [6] reported the lower apoptosis of intestinal epithelial cells, the main source of L-tryptophan for microbial indolic compound production, in the EMs fed a diet supplemented with 3% HTs.…”

Section: Introductionmentioning

confidence: 89%

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Effect of Supplementing Hydrolysable Tannins to a Grower–Finisher Diet Containing Divergent PUFA Levels on Growth Performance, Boar Taint Levels in Back Fat and Intestinal Microbiota of Entire Males

Tretola

Maghin

Silacci

et al. 2019

Animals

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A retrospective data analysis suggested that the levels of boar taint compounds depend on the polyunsaturated fatty acid (PUFA) level of the adipose tissue (AT) being significantly greater in the unsaturated AT. In addition, we recently reported that hydrolysable tannins (HTs) offered to entire males (EMs) reduce skatole and, to a greater extent, indole levels in the AT. Thus, the objective of the study was to determine the impact of HTs and a high dietary level of PUFA on growth performance and board taint compounds in EMs. In addition, the interaction between PUFA and HTs on gut microbiota and its link to intestinal skatole and indole production was investigated. At 25 kg BW, 44 EM originating from 11 litters were randomly assigned within litter to four dietary treatments. Two basal grower (25–60 kg BW) and finisher (60–105 kg BW) diets containing either 2% soy oil (H = high PUFA level) or 2% tallow (L = low PUFA level) were formulated. The H and L diets were either supplemented (H+/L+) or not (H−/L−) with 3% chestnut extract containing 50% HTs. The pigs had ad libitum access to the diets and were slaughtered at 170 days of age. The microbiota composition was investigated through the 16S rRNA gene sequences obtained by next-generation sequencing (Illumia MiSeq platform, San Diego, CA, USA) and analyzed with a specific packages in R, version 3.5.0. Regardless of the PUFA content, the EMs fed the H+ diets were 2% (p < 0.01) less feed efficient overall. This was due to the slower (p = 0.01) growth in the finisher period despite similar feed intake. Carcass characteristics were not affected by the diets. Regardless of HT feeding, the PUFA level in the AT of the H pigs was 10% greater (p = 0.05) than in the L pigs. The indole level tended (p = 0.08) to be 50% lower in the H+ group. Surprisingly, the pigs that were fed diet H− had greater skatole levels than those fed diet L−, with intermediate skatole levels in the H+ and L+. Independent of the PUFA level, the HTs decreased bacteria abundance and qualitatively affected the microbiota composition. In conclusion, these data do not confirm that boar taint compound levels were related to PUFA levels in the AT. However, HTs can be considered to be a promising alternative to conventional antibacterial additives, with no detrimental effects on pig gut health and with appealing properties for reducing the synthesis of the main components of boar taint.

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Section: Dietary Effects On Growth Performancesupporting

confidence: 88%

Section: Introductionmentioning

confidence: 89%

Effect of Supplementing Hydrolysable Tannins to a Grower–Finisher Diet Containing Divergent PUFA Levels on Growth Performance, Boar Taint Levels in Back Fat and Intestinal Microbiota of Entire Males

Tretola

Maghin

Silacci

et al. 2019

Animals

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“…A study in pigs for fattening traits has found that growth performance was not affected by the addition of 2000 mg TA/kg from sweet chestnut (Prevolnik et al, 2012). A similar study has investigated that average daily gain in piglets were unaffected with the supplementation of 1500 mg of a TA/kg feed, and no negative effects were observed on blood profile during 21 days trials (Bilić-Šobot et al, 2016). On the other hand, another similar study described that piglets fed 125, 250, 500 or 1,000 mg TA/kg diet had increased feed conversion ratio, reduced average daily gain, red blood cell count, and hematocrit respectively, under 28 days experiments (Lee et al, 2010).…”

Section: Role Of Tannins On Animal Productionmentioning

confidence: 99%

“…However, the effects were not clear at lower concentration. For animal husbandry application, the disadvantageous effects appear at 250 mg tannin/kg diet (Bilić-Šobot et al, 2016). A study on male rabbits in New Zealand has revealed that there was no deleterious effect associated with tannin supplementation as compared to control groups (without tannic acid (TA) from chestnut wood) under 21 days experiments (Liu et al, 2011(Liu et al, , 2012.…”

Section: Role Of Tannins On Animal Productionmentioning

confidence: 99%

Tannin Supplementation in Animal Feeding; Mitigation Strategies to Overcome the Toxic Effects of Tannins on Animal Health: A Review

Nawab¹,

Tang²,

Gao³

et al. 2020

JAS

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Optimum animal production depends on the type of feedstuffs available for the whole year. Plants such as trees and shrubs have significance in the animal production due to high nutritious values of tannins which reduce the rumen protein degradability and improve the feed digestibility as well as amino acid absorption in the small intestine. But, some of these plant materials are usually rich in anti-nutritional factors, known as tannins. Tannins are a complex group of plant secondary compounds widely distributed in the plant kingdom. Tannins have both deleterious and advantageous effects depending on the types, doses, composition and concentration of tannins. Rural farmers face fodder scarcity during the winter season. Therefore, tannins containing browse species may help farmers to use tannins as supplementary feed for livestock. But higher concentrations of tannins cause metabolic disorder which in results reduces the animal productivity. Therefore, it is need to investigate the effects of tannin supplementation in animal feeding; mitigation strategies to overcome the toxic effects of tannins on animal health. In this review paper, we have discussed safety and hazard associated with tannins in animal feeding.

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“…Similarly, chestnut tannins improved the antioxidant status of heat-stressed lambs [115] or the fatty acid composition of eggs [116] and reduced intestinal skatole production in pigs [117,118]. …”

Section: Main Applications Of Phenol-based Polymers In Food and Hementioning

confidence: 99%

Natural Phenol Polymers: Recent Advances in Food and Health Applications

Panzella

Napolitano

2017

Antioxidants

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Natural phenol polymers are widely represented in nature and include a variety of classes including tannins and lignins as the most prominent. Largely consumed foods are rich sources of phenol polymers, notably black foods traditionally used in East Asia, but other non-edible, easily accessible sources, e.g., seaweeds and wood, have been considered with increasing interest together with waste materials from agro-based industries, primarily grape pomace and other byproducts of fruit and coffee processing. Not in all cases were the main structural components of these materials identified because of their highly heterogeneous nature. The great beneficial effects of natural phenol-based polymers on human health and their potential in improving the quality of food were largely explored, and this review critically addresses the most interesting and innovative reports in the field of nutrition and biomedicine that have appeared in the last five years. Several in vivo human and animal trials supported the proposed use of these materials as food supplements and for amelioration of the health and production of livestock. Biocompatible and stable functional polymers prepared by peroxidase-catalyzed polymerization of natural phenols, as well as natural phenol polymers were exploited as conventional and green plastic additives in smart packaging and food-spoilage prevention applications. The potential of natural phenol polymers in regenerative biomedicine as additives of biomaterials to promote growth and differentiation of osteoblasts is also discussed.

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Effect of hydrolysable tannins on intestinal morphology, proliferation and apoptosis in entire male pigs

Cited by 54 publications

References 40 publications

Effect of Supplementing Hydrolysable Tannins to a Grower–Finisher Diet Containing Divergent PUFA Levels on Growth Performance, Boar Taint Levels in Back Fat and Intestinal Microbiota of Entire Males

Effect of Supplementing Hydrolysable Tannins to a Grower–Finisher Diet Containing Divergent PUFA Levels on Growth Performance, Boar Taint Levels in Back Fat and Intestinal Microbiota of Entire Males

Tannin Supplementation in Animal Feeding; Mitigation Strategies to Overcome the Toxic Effects of Tannins on Animal Health: A Review

Natural Phenol Polymers: Recent Advances in Food and Health Applications

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