Effect of Imiquimod as Compared With Surgery on the Cancerization Field in Basal Cell carcinoma

Graells, Jordi; Ojeda, R.M.; García-Cruz, A.

doi:10.1016/j.adengl.2013.09.001

Cited by 7 publications

(10 citation statements)

References 24 publications

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“…The hydrogels were stored in an incubator 25 for 24 h before being used for the preparation of the bigels. Imiquimod 5 was only dispersed in control hydrogel formulations HH1 and SH1 .…”

Section: Formulation Of the Hydrogelmentioning

confidence: 99%

Development and Physical Characterization of Polymer-Fish Oil Bigel (Hydrogel/Oleogel) System as a Transdermal Drug Delivery Vehicle

2014

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“…The hydrogels were stored in an incubator 25 for 24 h before being used for the preparation of the bigels. Imiquimod 5 was only dispersed in control hydrogel formulations HH1 and SH1 .…”

Section: Formulation Of the Hydrogelmentioning

confidence: 99%

Development and Physical Characterization of Polymer-Fish Oil Bigel (Hydrogel/Oleogel) System as a Transdermal Drug Delivery Vehicle

2014

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“…The analysis selected 782 studies, but only 21 were included based on the inclusion criteria. Of these, only two studies focused on surgical treatment (Graells et al, 2014) and of these one reported the use of cryosurgery (Berman et al, 2014). Both had a lower level of scientific evidence (level of evidence 4) (Howick et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Skin field cancerisation: A systematic review of the literature regarding its treatment

2020

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Introduction Skin neoplasms are the most frequent malignant lesions, increasing patient's morbidity when associated with skin field cancerisation. There is a need to understand the current therapies, both clinical and surgical. Methods A systematic review was performed according to the PRISMA guideline, registered in PROSPERO: CRD42018114826, including studies from 2012 to 2019. Results Seven hundred and eighty‐two studies were found, of which 21 were included. Of these, 8 primary studies were randomised controlled trials: fractional CO2 laser‐assisted photodynamic therapy (PDT) vs. PDT (no significance), daylight PDT vs. PDT (no significance, daylight PDT had less adverse effects), trichloroacetic acid peel vs. 5‐aminolaevulinic acid PDT (clinical improvement of aminolaevulinic acid PDT), 5‐Fluorouracil 0.5%/Salicylic Acid 10% vs. vehicle (clinical improvement of 5‐Fluorouracil 0.5%/Salicylic Acid 10%), photolyase vs. sun filters (no significance), sunscreens vs. sunscreens plus DNA repair enzymes (DNA Repair Enzymes was more effective in reducing field cancerisation). Only one systematic review was included in which there was effectiveness of daylight PDT in the treatment of actinic keratoses. The other 12 included studies had a lower level of evidence including surgical studies. Conclusion Clinical studies are more relevant in the treatment of the field cancerisation. There is a lack of surgical studies.

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“…1 Oral retinoids have been used for skin cancer prevention, alone or in combination with topical imiquimod, with good response. 2 Imiquimod has also been used to treat skin carcinomas in XP with a favourable response and no relapse after 2 years of follow-up. 3 A dramatic improvement of the skin appearance on the application site of imiquimod has been observed in patients with XP.…”

Section: Reversed Actinic Damage In Two Children With Xeroderma Pigmementioning

confidence: 99%

“…3 A dramatic improvement of the skin appearance on the application site of imiquimod has been observed in patients with XP. [2][3][4][5][6][7] We report two children with XP treated with imiquimod 5% cream, establishing a chemoprophylaxis for cancerization field.…”

Section: Reversed Actinic Damage In Two Children With Xeroderma Pigmementioning

confidence: 99%

“…Dear editor, Topical anaesthetics for the treatment of anal fissures or haemorrhoids are a frequent cause of allergic contact dermatitis (ACD) in the perianal region. 1 Since 2009, a few cases have been reported also to the calcium channel blocker (CCB) diltiazem [2][3][4] used as a first-line agent in the treatment of anal fissures. We present a case of ACD from diltiazem and/or cinchocaine followed by systemic contact dermatitis (SCD).…”

Section: Systemic Allergic Contact Dermatitis Associated With Topicalmentioning

confidence: 99%

See 1 more Smart Citation

Reversed actinic damage in two children with xeroderma pigmentosum treated with topical imiquimod

Latour

Hernández‐Martín

Ged

et al. 2018

Acad Dermatol Venereol

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Effect of Imiquimod as Compared With Surgery on the Cancerization Field in Basal Cell carcinoma

Cited by 7 publications

References 24 publications

Development and Physical Characterization of Polymer-Fish Oil Bigel (Hydrogel/Oleogel) System as a Transdermal Drug Delivery Vehicle

Development and Physical Characterization of Polymer-Fish Oil Bigel (Hydrogel/Oleogel) System as a Transdermal Drug Delivery Vehicle

Skin field cancerisation: A systematic review of the literature regarding its treatment

Reversed actinic damage in two children with xeroderma pigmentosum treated with topical imiquimod

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